Carbohydrate Structures in Targeted Drug Delivery
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (20 December 2024) | Viewed by 8805
Special Issue Editor
Interests: organic synthesis; medicinal chemistry; glycoconjugates; glicopeptides; ligand-receptor interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The development of safe and highly specific systems for targeted drug delivery is extremely important for improvements in drug therapy effectiveness. Different specialized drug carriers and delivery systems for active and passive drug targeting can be used, such as antibody–drug conjugates, liposomes, nanopolymers, and nanoparticles. Great efforts are being made to improve the selectivity of the targeted drug delivery, a complex process in which properties of the drug, drug carrier, and targeting site should be harmonized. Carbohydrates are natural molecules and have versatile roles in many biological events such as cellular communication, enzyme activities, infections, cancer metastases, and immune functions. Prominent advantages of carbohydrates are biodegradability, biocompatibility, hydrophilicity, and highly specific interaction with target receptors on the cell surface. Due to the above-mentioned characteristics, they are used for the preparation of systems for the targeted delivery of drugs, as well as for the sustained release of drugs, immune antigens, and adjuvants. Therefore, research on the role of carbohydrate structures in targeted drug delivery is needed to overcome drug delivery challenges and improve therapeutic outcomes.
This Special Issue is supervised by Dr. Rosana Ribić and assisted by our Topical Advisory Panel Member Dr. Rajendra Rohokale, rajendra.rohokal@chem.ufl.edu (Guo Research Group, University of Florida, Gainesville, FL, USA).
Dr. Rosana Ribić
Guest Editor
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Keywords
- carbohydrates
- targeted drug delivery
- drug–target interactions
- glycoconjugates
- glyconanoparticles
- lipid-based drug delivery systems
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