Advances in Oral Oncology

Dear Colleagues,

Head and neck cancer is the sixth most common cancer worldwide. Oral squamous cell carcinoma (OSCC) is the most common head and neck malignancy, characterized by a highly invasive capacity, lymph node metastasis, and high recurrence rate. Prognosis is poor, showing a 5-year survival rate of 50–60%. It is accepted that OSCC arises from multiple genetic alterations also related to risk factors such as alcohol, smoking, viral infections, and chronic inflammation. Oral premalignant lesions and conditions are precursors of OSCC. The molecular mechanisms of carcinogenesis, tumor progression, and metastasis of oral cancer have been elucidated by recent advances in molecular biology. However, many unsolved questions still remain.

This Special Issue entitled “Advances in Oral Oncology” has the objective of developing an updated investigation and rationale of biological behavior of oral squamous cell carcinoma focusing on molecular biology, pathology, biomarkers, genetics, diagnostics, and therapeutics. Scientific contributions regarding oral complications after cancer treatment will also be considered.

Prof. Dr. Amerigo Giudice
Guest Editor

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