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Bone and Joint Health and Rehabilitation
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Bone and Joint Health and Rehabilitation

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 16681

Special Issue Editors

Dr. Gerardo L. Garcés

E-Mail Website
Guest Editor
Department of Ciencias Médicas y Quirúrgicas, University of Las Palmas de Gran Canaria, 35016 Las Palmas, Spain
Interests: knee and hip joint reconstruction; sports medicine
Dr. Fernando M. Santonja-Medina

E-Mail Website
Guest Editor
Department of Surgery, Pediatrics, Obstetrics and Gynecology, Faculty of Medicine, University of Murcia, 30100 Murcia, Spain
Interests: sports medicine; muscle conditioning; hamstring shortening

Special Issue Information

Dear Colleagues,

With its different modalities, rehabilitation is an essential part of conservative and surgical treatment of bone and joint trauma and diseases. This special issue is devoted to rehabilitation to improve bone and joint health. We looked for papers about applying rehabilitation to treat bone disorders like fractures, osteoporosis, tumors, necrosis, and bone manifestations of metabolic diseases. Joint alterations to be considered in this issue are degenerative and inflammatory diseases, ligament ruptures, tumors, and posttraumatic conditions.

Rehabilitation techniques include all the modalities of physiotherapy to specifically treat body dysfunctions: manual therapy, physical therapy (ultrasound therapy, thermotherapy, cryotherapy, electrotherapy, dry-nealing, etc.), hydrotherapy, taping, massages. Research studies about muscle strength, muscle activation, and electromyography are also welcomed.

Dr. Gerardo L. Garcés
Dr. Fernando M. Santonja-Medina
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • rehabilitation
  • fracture
  • osteoporosis
  • bone tumor
  • osteoarthritis
  • rheumatoid arthritis
  • muscle strength

Published Papers (6 papers)

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10 pages, 1037 KiB  
Article
Bone Health Status in Individuals with Amyotrophic Lateral Sclerosis: A Cross-Sectional Study on the Role of the Trabecular Bone Score and Its Implications in Neurorehabilitation
by Elisabetta Morini, Simona Portaro, Danilo Leonetti, Maria Cristina De Cola, Rosaria De Luca, Mirjam Bonanno, Angelo Quartarone and Rocco Salvatore Calabrò
Int. J. Environ. Res. Public Health 2023, 20(4), 2923; https://doi.org/10.3390/ijerph20042923 - 07 Feb 2023
Cited by 2 | Viewed by 1676
Abstract
Background and Objectives: Osteoporosis is a metabolic skeletal disease resulting in low bone mass with increased bone fragility and susceptibility to fractures. May lead to rapid loss of bone mineral density (BMD) due to physical inactivity and reduced muscle contractions. Generally, the [...] Read more.
Background and Objectives: Osteoporosis is a metabolic skeletal disease resulting in low bone mass with increased bone fragility and susceptibility to fractures. May lead to rapid loss of bone mineral density (BMD) due to physical inactivity and reduced muscle contractions. Generally, the diagnosis of osteoporosis is made using dual X-ray absorptiometry (DXA), by measuring BMD and the trabecular bone score (TBS), which can be useful for detecting bone fragility and susceptibility to fractures. Therefore, the aim of this study was to investigate, using BMD and TBS, the bone health status in a sample of amyotrophic lateral sclerosis (ALS) inpatients attending neurorehabilitation. Materials and Methods: Thirty-nine patients were included in the study and underwent electrocardiogram and blood tests, including calcium and parathyroid hormone, as well as vitamin D dosage, and DXA. Results: We found that the TBS of patients with osteoporosis was lower than that of those ALS patients with osteopenia or normal bone status, both in the lumbar spine and femoral neck, although no statistical significance was reached. In addition, Spearman’s correlation coefficient indicated a moderate correlation between TBS and lumbar spine BMD (r = −0.34) and a mild correlation between TBS and femoral neck BMD (r = −0.28). Conclusions: This study confirmed the hypothesis that ALS patients may exhibit deteriorated bone health with lower bone density and focused on the possible role of the TBS in the multidisciplinary approach to ALS. Full article
(This article belongs to the Special Issue Bone and Joint Health and Rehabilitation)
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9 pages, 934 KiB  
Article
Clinical Use of Lansoprazole and the Risk of Osteoporosis: A Nationwide Cohort Study
by Ming-Hsuan Chung, Yong-Chen Chen, Wen-Tung Wu, Ming-Hsun Lin, Yun-Ju Yang, Dueng-Yuan Hueng, Tsung-Kun Lin, Yu-Ching Chou and Chien-An Sun
Int. J. Environ. Res. Public Health 2022, 19(22), 15359; https://doi.org/10.3390/ijerph192215359 - 21 Nov 2022
Cited by 1 | Viewed by 2082
Abstract
Background: Proton pump inhibitor (PPI) lansoprazole acts as a liver X receptor agonist, which plays a crucial role in the crosstalk of osteoblasts and osteoclasts in vitro and during bone turnover in vivo. However, epidemiological studies on the association between the use of [...] Read more.
Background: Proton pump inhibitor (PPI) lansoprazole acts as a liver X receptor agonist, which plays a crucial role in the crosstalk of osteoblasts and osteoclasts in vitro and during bone turnover in vivo. However, epidemiological studies on the association between the use of lansoprazole and osteoporosis risk are limited. We aimed to determine the risk of developing osteoporosis in patients with lansoprazole use. Methods: A retrospective cohort study was conducted using the National Health Insurance Research Database of Taiwan dated from 2000 to 2013. The study includes 655 patients with lansoprazole use (the exposed cohort) and 2620 patients with other PPI use (the comparison cohort). The main outcome was the primary diagnosis of osteoporosis. The hazard ratios (HRs) and 95% confidence intervals (CIs) were used to assess the association between the use of lansoprazole and risk of osteoporosis. Results: Patients receiving lansoprazole treatment had a reduced risk of osteoporosis as compared with those undergoing other PPI therapy (adjusted HR, 0.56; 95% CI, 0.46–0.68). Moreover, this inverse association is evident in both sexes and in various age groups. Conclusions: This population-based cohort study demonstrated that lansoprazole use was associated with a reduced risk of osteoporosis. The clinical implications of the present study need further investigations. Full article
(This article belongs to the Special Issue Bone and Joint Health and Rehabilitation)
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15 pages, 1423 KiB  
Article
Association of Short-Term Changes in Menstrual Frequency, Medication Use, Weight and Exercise on Bone Mineral Density in College-Aged Women
by Stacie H. Fleischer, Annalisa K. Freire, Katie Brown, Andrew Creer, Dennis L. Eggett and Susan Fullmer
Int. J. Environ. Res. Public Health 2022, 19(16), 10363; https://doi.org/10.3390/ijerph191610363 - 19 Aug 2022
Viewed by 1405
Abstract
To evaluate if experiencing a short-term exposure (18-months) to factors such as menstrual irregularities, dieting, changes in exercise or body weight, and medication usage is associated with bone mineral density (BMD) in college-aged females. A retrospective survey assessing health behaviors during a recent [...] Read more.
To evaluate if experiencing a short-term exposure (18-months) to factors such as menstrual irregularities, dieting, changes in exercise or body weight, and medication usage is associated with bone mineral density (BMD) in college-aged females. A retrospective survey assessing health behaviors during a recent 18-month time period and a DXA scan were completed in 641 females. A total of 45.5% of participants reported amenorrhea during the 18-month time period. Those who experienced amenorrhea had lower femoral neck BMD (p = 0.018), trochanter (p = 0.018) and spine BMD (p = 0.022) compared to eumenorrheic women. Lifetime oral contraceptive usage longer than six months was negatively associated with BMD at femoral neck (p = 0.018) and total hip (p = 0.021). Women who lost weight trended towards having the lowest BMD at all sites compared to women who gained weight. Following a very-low calorie diet during the time period was negatively correlated with spine BMD (p = 0.001). Time spent in vigorous and very vigorous activity was weakly correlated with some hip BMD sites but time spent in extremely vigorous activity was not. In conclusion, females who experienced weight loss, amenorrhea, or a very low-calorie diet within an 18-month period of time in young adulthood had lower BMD. Additionally, oral contraceptive usage for longer than six months during their lifetime was associated with lower BMD. Full article
(This article belongs to the Special Issue Bone and Joint Health and Rehabilitation)
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12 pages, 1211 KiB  
Article
Validity and Absolute Reliability of the Cobb Angle in Idiopathic Scoliosis with TraumaMeter Software
by José Hurtado-Avilés, Fernando Santonja-Medina, Vicente J. León-Muñoz, Pilar Sainz de Baranda, Mónica Collazo-Diéguez, Mercedes Cabañero-Castillo, Ana B. Ponce-Garrido, Victoria Eugenia Fuentes-Santos, Fernando Santonja-Renedo, Miriam González-Ballester, Francisco Javier Sánchez-Martínez, Pietro Gino Fiorita, Jose Manuel Sanz-Mengibar, Joaquín Alcaraz-Belzunces, Vicente Ferrer-López and Pilar Andújar-Ortuño
Int. J. Environ. Res. Public Health 2022, 19(8), 4655; https://doi.org/10.3390/ijerph19084655 - 12 Apr 2022
Cited by 7 | Viewed by 2550
Abstract
The Cobb angle value is a critical parameter for evaluating adolescent idiopathic scoliosis (AIS) patients. This study aimed to evaluate a software’s validity and absolute reliability to determine the Cobb angle in AIS digital X-rays, with two different degrees of experienced observers. Four [...] Read more.
The Cobb angle value is a critical parameter for evaluating adolescent idiopathic scoliosis (AIS) patients. This study aimed to evaluate a software’s validity and absolute reliability to determine the Cobb angle in AIS digital X-rays, with two different degrees of experienced observers. Four experts and four novice evaluators measured 35 scoliotic curves with the software on three separate occasions, one month apart. The observers re-measured the same radiographic studies on three separate occasions three months later but on conventional X-ray films. The differences between the mean bias errors (MBE) within the experience groups were statistically significant between the experts (software) and novices (manual) (p < 0.001) and between the novices (software) and novices (manual) (p = 0.005). When measured with the software, the intra-group error in the expert group was MBE = 1.71 ± 0.61° and the intraclass correlation coefficient (ICC (2,1)) = 0.986, and in the novice group, MBE = 1.9 ± 0.67° and ICC (2,1) = 0.97. There was almost a perfect concordance among the two measurement methods, ICC (2,1) = 0.998 and minimum detectable change (MCD95) < 0.4°. Control of the intrinsic error sources enabled obtaining inter- and intra-observer MDC95 < 0.5° in the two experience groups and with the two measurement methods. The computer-aided software TraumaMeter increases the validity and reliability of Cobb angle measurements concerning manual measurement. Full article
(This article belongs to the Special Issue Bone and Joint Health and Rehabilitation)
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13 pages, 995 KiB  
Protocol
Transcutaneous Vagal Stimulation in Knee Osteoarthritis (TRAVKO): Protocol of a Superiority, Outcome Assessor- and Participant-Blind, Randomised Controlled Trial
by Claudio Bascour-Sandoval, Rubén Gajardo-Burgos, Claudio Muñoz-Poblete, Pablo Riedemann-González, Stephanie Erices-Salas, Agustín Martínez-Molina and Germán Gálvez-García
Int. J. Environ. Res. Public Health 2023, 20(1), 311; https://doi.org/10.3390/ijerph20010311 - 25 Dec 2022
Cited by 1 | Viewed by 1584
Abstract
Current treatments for knee osteoarthritis (KOA) are partially effective. It is, therefore, necessary to find new strategies that can complement the existing ones. In this scenario, transcutaneous vagal stimulation (TVS) neurophysiological effects could be a helpful solution. However, there is no evidence of [...] Read more.
Current treatments for knee osteoarthritis (KOA) are partially effective. It is, therefore, necessary to find new strategies that can complement the existing ones. In this scenario, transcutaneous vagal stimulation (TVS) neurophysiological effects could be a helpful solution. However, there is no evidence of the efficacy of TVS in KOA. This trial aims to assess the efficacy of TVS in decreasing pain in participants aged 55 years or older with KOA. A randomised controlled, two-arm, double-blind (participants and outcome assessors) and clinical superiority trial will be conducted for 70 patients with KOA. All the participants will carry out an exercise program. It consists of 12 sessions over four weeks. In addition, they will be randomly assigned to (1) active TVS plus physical exercise or (2) sham TVS plus physical exercise. The application of active TVS consists of electronic stimulation of the auricular concha using a portable device. Sham TVS condition consists of the stimulation of the earlobe that does not cause neurophysiological effects. The primary outcome is the reduction in pain intensity. Additionally, functional capacity, physical performance, pain-related interference, pain-related distress, quality of life in older adults and global change will be measured. Assessments will be conducted at the beginning of the study (baseline), at the end of the intervention and after 1 and 3 months of follow-up. This trial will generate evidence regarding the efficacy of TVS in pain perception in individuals with KOA. This information will serve as an input in the clinical decision-making on the use or non-use of TVS in individuals with KOA. Thus, if the efficacy of TVS is confirmed, a new therapeutic tool may be included in the rehabilitation of individuals with KOA. Full article
(This article belongs to the Special Issue Bone and Joint Health and Rehabilitation)
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17 pages, 728 KiB  
Systematic Review
Effects of Patient Education on Pain and Function and Its Impact on Conservative Treatment in Elderly Patients with Pain Related to Hip and Knee Osteoarthritis: A Systematic Review
by Pierluigi Sinatti, Eleuterio A. Sánchez Romero, Oliver Martínez-Pozas and Jorge H. Villafañe
Int. J. Environ. Res. Public Health 2022, 19(10), 6194; https://doi.org/10.3390/ijerph19106194 - 19 May 2022
Cited by 36 | Viewed by 6733
Abstract
(1) Background: Patient education (PE), exercise therapy, and weight management are recommended as first-line interventions for hip and knee osteoarthritis (OA). Evidence supporting the effectiveness of exercise therapy and weight management in people with lower-limb OA has been synthesized in recent studies. However, [...] Read more.
(1) Background: Patient education (PE), exercise therapy, and weight management are recommended as first-line interventions for hip and knee osteoarthritis (OA). Evidence supporting the effectiveness of exercise therapy and weight management in people with lower-limb OA has been synthesized in recent studies. However, according to the Osteoarthritis Research Society International, PE is often considered a standard of care and the inclusion of this as a first-line intervention for people with knee OA in clinical practice guidelines is often supported by limited evidence. The aim of this review is to evaluate the effects of PE on pain and function and how it impacts on conservative treatment. (2) Methods: This is a literature review of studies investigating the effect of patient education on pain and function and its impact on conservative treatment in elderly patients with pain related to hip and knee OA. PRISMA guidelines were followed during the design, search, and reporting stages of this review. The search was carried out in the PubMed database. (3) Results: A total of 1732 studies were detected and analyzed by performing the proposed searches in the detailed database. After removing duplicates and analyzing the titles and abstracts of the remaining articles, 20 studies were ultimately selected for this review. Nineteen of these twenty articles showed positive results in pain or function in patients with pain related to hip and knee OA. (4) Conclusions: PE seems to be effective in reducing pain and improving function in patients with pain related to hip and knee OA. Furthermore patient education seems to positively impact the conservative treatment with which it can be associated. Full article
(This article belongs to the Special Issue Bone and Joint Health and Rehabilitation)
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