Chemical Regulators in Horticulture: Seed Germination, Propagation and Metabolic Enhancement of Medicinal Plants

A special issue of Horticulturae (ISSN 2311-7524). This special issue belongs to the section "Medicinals, Herbs, and Specialty Crops".

Deadline for manuscript submissions: 20 June 2026 | Viewed by 309

Special Issue Editors


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Guest Editor
College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China
Interests: medicinal plants; plant secondary metabolism; synthetic biology

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Guest Editor
College of Horticulture, Nanjing Agricultural University, Nanjing, China
Interests: growth and quality control of medicinal plants

Special Issue Information

Dear Colleagues,

The sustainable cultivation of medicinal plants is essential to meet increasing global demand while conserving wild genetic resources. A major challenge in this process lies in the early stages of production, including seed dormancy, low germination rates, and inefficient propagation systems, which limit the availability of high-quality planting material. Furthermore, ensuring consistent and enhanced accumulation of bioactive metabolites under cultivated conditions remains a critical goal. The targeted application of chemical regulators, such as plant hormones, exogenous elicitors, and signaling molecules, offers a promising approach to overcome these bottlenecks. This Special Issue highlights the role of such regulators in optimizing key horticultural traits, from seed establishment to secondary metabolism.

This Special Issue will present innovative research on the use of chemical regulators to improve medicinal plant production. We invite studies focusing on breaking seed dormancy, enhancing seed germination, refining in vitro propagation and micropropagation protocols, and inducing the biosynthesis of target secondary metabolites. Contributions may also include work on the role of regulators in improving abiotic stress tolerance and their integration with controlled environment horticulture. We welcome articles that provide mechanistic insights or practical applications aimed at achieving high germination efficiency, rapid clonal multiplication, and elevated phytochemical quality in medicinal plants.

Prof. Dr. Dongfeng Yang
Prof. Dr. Zaibiao Zhu
Guest Editors

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Keywords

  • medicinal plants
  • seed dormancy
  • plant growth regulators
  • elicitors
  • plant tissue culture
  • in vitro propagation
  • bioactive constituents
  • plant hormones
  • metabolic enhancement

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Published Papers (1 paper)

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Research

18 pages, 2290 KB  
Article
Magnesium Hydride Enhances Both Growth and Bioactive Compound Biosynthesis in Salvia miltiorrhiza: A Novel Eco-Friendly Approach for Medicinal Plant Cultivation
by Wei Li, Youran Zeng, Jingjing Li, Xinru Du, Yang Liu, Yihong Li, Haiyan Yang, Gurusamy Abirami, Itezaz Younas, Han Zheng and Dongfeng Yang
Horticulturae 2025, 11(12), 1499; https://doi.org/10.3390/horticulturae11121499 - 11 Dec 2025
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Abstract
Medicinal plants have garnered widespread attention owing to their broad range of biological activities and pharmaceutical value. However, achieving a balance between promoting plant growth and enhancing bioactive compound accumulation remains a major challenge in current research. In this study, Salvia miltiorrhiza was [...] Read more.
Medicinal plants have garnered widespread attention owing to their broad range of biological activities and pharmaceutical value. However, achieving a balance between promoting plant growth and enhancing bioactive compound accumulation remains a major challenge in current research. In this study, Salvia miltiorrhiza was selected as the model organism to investigate the effects of MgH2 on growth and the accumulation of bioactive compounds. Our results demonstrated that MgH2 treatment at 10.0 mg kg−1 soil increased the seed germination rate by 49.3%. At the optimal concentration of 12.5 mg kg−1 soil, MgH2 significantly promoted seedling growth, enhancing root biomass by 745.6% after 4 weeks of treatment. Furthermore, MgH2 application dramatically boosted the accumulation of bioactive compounds, increasing the total content of rosmarinic acid and dihydrotanshinone by 1271.8% and 2407.7%, respectively. Transcriptome analysis revealed that these improvements were associated with the upregulation of genes involved in plant hormone signal transduction, energy metabolism, and the biosynthesis pathways of tanshinones and salvianolic acids. Our findings provide the first evidence that MgH2 acts as a dual-functional regulator, simultaneously enhancing both plant growth and secondary metabolite accumulation in medicinal plants, offering a green and efficient cultivation strategy for the sustainable production of high-quality S. miltiorrhiza. Full article
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