Algae as a Potential Source of Food Components: Bioactive Ingredients, New Products Development and Sustainability

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Nutraceuticals, Functional Foods, and Novel Foods".

Deadline for manuscript submissions: 9 October 2026 | Viewed by 1676

Special Issue Editors


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Guest Editor
Department of Food Science, Aarhus University, AgroFood Park 48, N 8200 Aarhus, Denmark
Interests: marine algae; lipid chemistry; food quality; bioactive compounds; bio-based active packaging
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Food Science, Aarhus University, AgroFood Park 48, N 9200 Aarhus, Denmark
Interests: biocatalysis; bioactivity; algal biomass; green chemistry; bioactive compounds; microbiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Population growth, food demand, and climate footprint are major challenges in our society. Our current food system relies on unsustainable intensive agriculture, and unlike terrestrial crops, marine organisms thrive in aquatic environments, require no land, and possess unique, biologically active biomaterials. Macro- and microalgae represent a sustainable and resilient bioresource with untapped opportunities for food innovation in nutritional enhancement, meeting sustainability and healthy food goals. In fact, the European Green Deal and the Sustainable Blue Economy Communication emphasize the algae sector as a bioresource of secured supply of raw biomaterials with a low-carbon footprint and a positive impact on preserving and restoring the ocean biodiversity. Yet, multifaceted challenges in the analytical characterization of the chemical structures of algae components, their efficient extraction, and stability bioavailability, as well as bioactivity after incorporation in a complex food system, still hinder their exploitation. In this scenario, this Special Issue focuses on the characterization, extraction, and incorporation of algae components as novel components for the food industry. Contributions to this Special Issue, both in the form of original research or review articles, cover all aspects from characterization, extraction, and purification of algae components; advancements in analytical methods for algae compounds evaluation; as well as incorporation of algae components as part of a complex food system. Articles regarding the influence of processing methods on their quality, including, but not limited to, their digestibility, functional properties, and aroma and flavor characteristics of novel food products, are also welcome.

Dr. Natalia Prieto Vidal
Dr. Maria Paz Garcia Garcia
Guest Editors

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Keywords

  • algae components extraction
  • food nutritional value
  • algae-based foods
  • sustainable foods
  • bioactive compounds
  • functional food
  • green chemistry in algae processing
  • algal oils
  • marine-derived food ingredients
  • circular food systems

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Published Papers (1 paper)

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Research

25 pages, 5031 KB  
Article
Comparative Metabolite Profiling and Antiproliferative Characterization of Lab-Acclimatized and Wild Green Seaweed Acrosiphonia orientalis to Reveal Its Nutraceutical Potential
by Deepesh Khandwal, Jalak N. Maniar, Shruti Kumari, Pratishtha Menaria and Avinash Mishra
Foods 2026, 15(7), 1252; https://doi.org/10.3390/foods15071252 - 6 Apr 2026
Viewed by 726
Abstract
The increasing demand for different value-added products from natural seaweeds requires a sustainable cultivation method for the regular supply of biomass and to safeguard the natural ecosystem from overexploitation. This study evaluated laboratory acclimatization of the green seaweed Acrosiphonia orientalis (DGR: 2.71 ± [...] Read more.
The increasing demand for different value-added products from natural seaweeds requires a sustainable cultivation method for the regular supply of biomass and to safeguard the natural ecosystem from overexploitation. This study evaluated laboratory acclimatization of the green seaweed Acrosiphonia orientalis (DGR: 2.71 ± 0.21%; GPP: 12.55 ± 0.1 mg O2 L−1 day−1), followed by a comparative evaluation of its physicochemical and biochemical characteristics, metabolite profile, and antiproliferative activity compared with naturally harvested seaweed. Metabolite profiling identified 47 compounds exhibiting differential accumulation patterns, with the natural specimens enriched in omega-3 polyunsaturated fatty acids, including docosahexaenoic acid, and the laboratory-acclimatized specimens exhibited elevated arachidonic acid levels. Amino acid profiling revealed higher concentrations of essential and non-essential amino acids in the natural specimens, with prominent levels of phenylalanine and aspartic acid, while the lab-acclimatized specimens were enriched in isoleucine, methionine, proline, and cysteine. The lab-acclimatized specimens exhibited significantly enhanced water absorption (WSC: 6 ± 0.25 mL/g DW; WHC: 2.68 ± 0.11 g/g DW) and higher total sugar (47.11 ± 0.52% Glc eq. DW) and phenolic contents (51.28 ± 0.54 mg GAE g−1 extract), while the natural specimens had a superior oil-holding capacity (OHC: 1.8 ± 0.12 g/g DW); higher total flavonoid (123.62 ± 2.97 mg Q g−1 extract), protein (5.11 ± 0.36 µg BSA eq/mg DW), and chlorophyll contents (8.82 ± 0.58 mg/L); and higher antioxidant activities (ABTS-EC50: 67.33 ± 0.97 μg/mL extract). The mineral analysis revealed distinct elemental profiles, with enrichment of sodium, magnesium, and calcium in the lab-acclimatized specimens and a more favorable Na/K ratio (0.14 vs. 0.78) in the natural specimens. Of note, extracts from both seaweeds exhibited significant dose-dependent antiproliferative activity against HeLa cervical cancer cells (Wild EC50: 118.63 ± 14.14 µg/mL extract; lab EC50: 153.35 ± 10.18 µg/mL extract), suppressed colony formation in soft agar assays, induced nuclear condensation (based on Hoechst staining), and modulated the expression of key oncogenes (upregulating NDRG1, TP53, and CASP3 and downregulating BCL2, MYC, and CCND1). Collectively, this study provides an approach to acclimatize A. orientalis that may be utilized for developing a cultivation method. Moreover, this green seaweed has a great potential to be used for nutraceutical and functional food applications. Full article
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