Novel Strategies and Emerging Technologies in Functional and Sustainable Food Systems

A Special Issue of Fermentation (ISSN 2311-5637) belonging to the section "Fermentation for Food and Beverages".

Deadline for manuscript submissions: closed (30 April 2026) | Viewed by 18261

Editors


E-Mail Website
Guest Editor
Laboratory of Applied Microbiology & Biotechnology, Department of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece
Interests: food microbiome; functional foods; fermented foods and beverages; food bioprocesses; agro-industrial and food waste valorization; circular economy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Today, we are facing multiple innovations in functional and sustainable food systems, aligning with the key priorities outlined in bioeconomy strategies, including the Sustainable Development Goals (SDGs) and the European Green Deal. Hence, designing novel foods and stable starter cultures which impact human health and food bioprocesses based on circular economy principles lies at the heart of food innovation. These objectives constitute the core focus of the “Infrastructure of Microbiome Applications in Food Systems – FOODBIOMES”, a Greek research infrastructure committed to developing microbiome applications that transform food systems and drive progress in human health and food sustainability.

As this Special Issue aims to highlight recent advances and novel findings related to health-promoting and sustainable food systems, we invite submissions covering topics that include, but are not limited to, the following:

  • Advances in fermentation technologies;
  • Innovations in developing stable functional cultures for food fermentation;
  • Microbiome applications in functional food development and consumer health;
  • Microbial diversity in fermented foods;
  • Dietary intervention studies linking food microbiome to health outcomes;
  • Novel strategies and emerging technologies for food security;
  • Sustainable food bioprocesses and circular economy principles;
  • Regulatory issues in functional foods.

Dr. Yiannis Kourkoutas
Dr. Gregoria Mitropoulou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • starter cultures
  • fermented foods and beverages
  • functional ingredients
  • dairy products
  • probiotics
  • prebiotics
  • synbiotics
  • sustainable processes
  • microbiome applications
  • food security
  • circular economy
  • functional food regulations

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Review

26 pages, 1941 KB  
Article
Immobilized Plant-Based Presumptive Probiotics as Functional Ingredients for Breakfast Cereals
by Chrysoula Pavlatou, Ioanna Prapa, Electra Stylianopoulou, Gregoria Mitropoulou, George Skavdis and Yiannis Kourkoutas
Fermentation 2025, 11(6), 335; https://doi.org/10.3390/fermentation11060335 - 10 Jun 2025
Cited by 4 | Viewed by 2480
Abstract
Seven wild-type lactic acid bacteria, belonging to Lactiplantibacillus plantarum and Lactococcus cremoris species, were isolated from beetroots and white mushrooms and evaluated for their safety and functional profile. Lc. cremoris isolates were sensitive to all antibiotics tested, while L. plantarum strains exhibited resistance in [...] Read more.
Seven wild-type lactic acid bacteria, belonging to Lactiplantibacillus plantarum and Lactococcus cremoris species, were isolated from beetroots and white mushrooms and evaluated for their safety and functional profile. Lc. cremoris isolates were sensitive to all antibiotics tested, while L. plantarum strains exhibited resistance in certain antibiotics. Among them, Lc. cremoris FBMS_5810 showed the highest cholesterol removal ability (51.89%) and adhesion capacity to Caco-2 cell lines (32.14%), while all plant origin strains exhibited strong antagonistic and inhibitory activity against foodborne pathogens, as well as high survival potential during an in vitro digestion model. Subsequently, freeze-dried immobilized Lc. cremoris FBMS_5810 cells on oat flakes were prepared with initial cell loads >8.5 log CFU/g, and the effect of trehalose as a cryoprotectant in cell viability during storage at room and refrigerated temperatures for up to 180 days was studied. A significant reduction in cell loads was observed in all cases studied. However, freeze-dried immobilized Lc. cremoris FBMS_5810 cells on oat flakes prepared using trehalose as a cryoprotectant stored at 4 °C exhibited the highest cell viability (8.75 log CFU/g) after 180 days. In the next step, functional breakfast cereals enriched with freeze-dried immobilized Lc. cremoris FBMS_5810 cells on oat flakes (produced with (MLT) or without (ML) trehalose) were developed and stored at room and refrigerated temperatures for 180 days. The initial cell levels ≥ 9.18 log CFU/g were achieved, while a significant decrease was recorded during storage in all cases. The maintenance of cell loads ≥ 7.75 log CFU/g was documented in the case of both ML and MLT samples stored at 4 °C; however, the presence of trehalose in MLT samples resulted in cell viability 7.52 log CFU/g after 180 days of storage at room temperature. Importantly, the functional breakfast cereals were accepted by the panel during the sensory evaluation. Full article
Show Figures

Graphical abstract

Review

Jump to: Research

32 pages, 449 KB  
Review
Fermenting the Unused: Microbial Biotransformation of Food Industry By-Products for Circular Bioeconomy Valorisation
by Elsa M. Gonçalves, José M. Pestana and Nuno Alvarenga
Fermentation 2026, 12(2), 73; https://doi.org/10.3390/fermentation12020073 - 28 Jan 2026
Cited by 11 | Viewed by 3332
Abstract
The food industry generates large volumes of nutrient-rich by-products that remain underutilised despite their considerable biochemical potential. These materials originate predominantly from the fruit and vegetable, dairy, meat, and fish and seafood sectors and represent a substantial opportunity for sustainable valorisation. Fermentation has [...] Read more.
The food industry generates large volumes of nutrient-rich by-products that remain underutilised despite their considerable biochemical potential. These materials originate predominantly from the fruit and vegetable, dairy, meat, and fish and seafood sectors and represent a substantial opportunity for sustainable valorisation. Fermentation has emerged as a powerful platform for converting such by-products into high-value ingredients, including bioactive compounds, functional metabolites, enzymes, antimicrobials, and nutritionally enriched fractions. This review synthesises recent advances in microbial fermentation strategies—spanning lactic acid bacteria, filamentous fungi, yeasts, and mixed microbial consortia—and highlights their capacity to enhance the bioavailability, stability, and functionality of recovered compounds across diverse substrate streams. Key technological enablers, including substrate pre-treatments, precision fermentation, omics-guided strain selection and improvement, and bioprocess optimisation, are examined within the broader framework of circular bioeconomy integration. Despite significant scientific progress, major challenges remain, particularly related to substrate heterogeneity, process scalability, regulatory alignment, safety assessment, and consumer acceptance. The review identifies critical research gaps and future directions, emphasising the need for standardised analytical frameworks, harmonised compositional databases, AI-driven fermentation control, integrated biorefinery concepts, and pilot-scale validation. Overall, the evidence indicates that integrated fermentation-based approaches—especially those combining complementary by-product streams, tailored microbial consortia, and system-level process integration—represent the most promising pathway toward the scalable, sustainable, and economically viable valorisation of food industry by-products. Full article
Show Figures

Graphical abstract

25 pages, 1691 KB  
Review
Microbial Poly-Glutamic Acid: Production, Biosynthesis, Properties, and Their Applications in Food, Environment, and Biomedicals
by Verma Manika, Palanisamy Bruntha Devi, Sanjay Pratap Singh, Geereddy Bhanuprakash Reddy, Digambar Kavitake and Prathapkumar Halady Shetty
Fermentation 2025, 11(4), 208; https://doi.org/10.3390/fermentation11040208 - 10 Apr 2025
Cited by 16 | Viewed by 11681
Abstract
This review offers an in-depth analysis of microbial γ-poly-glutamic acid (γ-PGA), highlighting its production, biosynthetic pathways, unique properties, and extensive applications in the food and health industries. γ-PGA is a naturally occurring biopolymer synthesized by various microorganisms, particularly species of Bacillus. The [...] Read more.
This review offers an in-depth analysis of microbial γ-poly-glutamic acid (γ-PGA), highlighting its production, biosynthetic pathways, unique properties, and extensive applications in the food and health industries. γ-PGA is a naturally occurring biopolymer synthesized by various microorganisms, particularly species of Bacillus. The report delves into the challenges and advancements in cost-effective production strategies, addressing the economic constraints associated with large-scale γ-PGA synthesis. Its biocompatibility, biodegradability, and non-toxic nature make it a promising candidate for diverse industrial applications. γ-PGA’s exceptional water-holding capacity and humectant properties are key to its utility in the food industry. These features enable it to enhance the stability, viscosity, and shelf life of food products, making it a valuable ingredient in processed foods. The review highlights its ability to improve the textural quality of baked goods, stabilize emulsions, and act as a protective agent against staling. Beyond food applications, γ-PGA’s role in health and pharmaceuticals is equally significant. Its use as a drug delivery carrier, vaccine adjuvant, and biofilm inhibitor underscores its potential in advanced healthcare solutions. Full article
Show Figures

Figure 1

Back to TopTop