Producing Lipids and Lipid Derivatives by Fermentation Using Agro-Industrial By-Products as Substrates

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Industrial Fermentation".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 210

Special Issue Editor


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Guest Editor
Laboratoire Transformations Intégrées de la Matière Renouvelable (UTC/ESCOM, EA 4297 TIMR), Ecole Supérieure de Chimie Organique et Minérale, 1 Allée du réseau Jean-Marie Buckmaster, 60200 Compiègne, France
Interests: fermentation; emerging processing technologies; valorization of by-products and agro-industrial waste bioprocesses; antioxidant bioactive compounds
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Special Issue Information

Dear Colleagues,

The global demand for sustainable eco-friendly production processes for bio-based chemicals and materials has driven significant advancements in white biotechnology. This Special Issue focuses on the innovative use of agro-industrial waste and by-products as substrates for microbial fermentation to produce lipids and their derivatives. By converting these side streams from agriculture and industry into high-value compounds, especially lipids and their derivatives, this approach addresses waste management challenges and contributes to the circular bioeconomy.

Works in this Special Issue will explore both upstream and downstream processes, including studying microbial pathways, their engineering, and bioprocess optimization, varying the sources of substrate by-products, extracting lipids and transforming them. These products offer sustainable alternatives to conventional lipid production from fossil fuels or edible crops.

Given the above potential and developments, Fermentation is inviting authors to submit unpublished original contributions, critical review articles, and short communications for consideration in this Special Issue on “Producing Lipids and Lipid Derivatives by Fermentation Using Agro-Industrial By-Products as Substrates”. The topics covered in this Special Issue include but are not limited to the following:

  • Fermentation strategies using agro-industrial waste and by-products as substrates;
  • Genetic engineering for a better assimilation of these non-conventional substrates by microorganisms;
  • Liquid- and solid-state fermentation for the production of lipids and their derivatives;
  • Extraction of lipids and their derivatives;
  • Microbial lipids’ transformation into products with a higher added value;
  • Applications of microbial lipids and their derivatives.

Dr. Mohamed Koubaa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fermentation
  • low-cost substrate transformation
  • white biotechnology
  • genetic engineering
  • extraction
  • chemical transformation of microbial lipids
  • high-value-added compounds

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Published Papers (1 paper)

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Research

18 pages, 3307 KiB  
Article
Olive Pruning: Waste or Growth Media? Expanding the Metabolic Potential of Phyllospheric Rhodococcus sp. 24CO
by Natalia E. Sandoval, Margarita Gomila, Nadia S. Arias, Héctor M. Alvarez and Mariana P. Lanfranconi
Fermentation 2025, 11(5), 237; https://doi.org/10.3390/fermentation11050237 - 23 Apr 2025
Viewed by 226
Abstract
Rhodococcus sp. 24CO, isolated from the olive phyllosphere, can accumulate significant amounts of neutral lipids, making it a promising candidate for biomass production from olive pruning waste. The strain efficiently converts this residue to neutral lipids, achieving a yield of over 20% of [...] Read more.
Rhodococcus sp. 24CO, isolated from the olive phyllosphere, can accumulate significant amounts of neutral lipids, making it a promising candidate for biomass production from olive pruning waste. The strain efficiently converts this residue to neutral lipids, achieving a yield of over 20% of the cellular dry weight (CDW). This indicates that olive leaves, a by-product of the olive oil industry, could become a valuable resource for both the economy and the environment. Genome analysis revealed various metabolic pathways for converting carbon sources to neutral lipids, while phenotypic studies showed that the strain is selective about its carbon sources, thriving on specific monosaccharides and polyols found in olive leaves. Notably, fructose and mannitol were rapidly metabolized, leading to a content of stored triacylglycerides of up to 47% and 28% of the CDW, respectively. The strain also exhibited oleagenicity under high nitrogen availability when grown on mannitol. Finally, potential oleagenicity determinants were explored through an omics comparison. Full article
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