Interpretable AI and Electronic System for Digital Health Biomarkers: From Sensing to Monitoring

A special issue of Electronics (ISSN 2079-9292). This special issue belongs to the section "Artificial Intelligence".

Deadline for manuscript submissions: 15 May 2026 | Viewed by 17

Special Issue Editors


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Guest Editor
Department of Control and Computer Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy
Interests: AI; machine learning; human pose estimation; human-computer interaction; neurodegenerative

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Guest Editor
Institute of Electronics, Computer and Telecommunication Engineering (IEIIT), National Research Council (CNR), Corso Duca degli Abruzzi 24, 10129 Torino, Italy
Interests: human motion analysis; telemedicine; computer vision for digital health; neurosciences; markerless body tracking; human–machine interfaces; exergames for rehabilitation; biosignals for stress and engagement assessments; artificial intelligence
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Guest Editor
Department of Informatics and Telecommunications, University of Ioannina, 47100 Arta, Greece
Interests: EEG signal processing and machine learning; particularly in dementia diagnosis; BCI applications; medical image analysis and classification

Special Issue Information

Dear Colleagues,

This Special Issue calls for advances that make AI-driven digital biomarkers for health monitoring transparent, interpretable, trustworthy, and clinically actionable across the clinic–home continuum. We seek contributions that turn raw clinical data into interpretable evidence at every step, from data curation and harmonization to model development, explanation, and prospective evaluation in real workflows. Target applications include early detection and risk stratification, differential diagnosis, disease staging and progression modeling, patient-specific prognosis, and monitoring of treatment response. Modalities span structural and molecular imaging (MRI/PET), biosignals (EEG/ECG/EMG/GSR), speech and handwriting, gait and kinematics, ocular/retinal measures, and multimodal wearables/smartphones digital biomarkers, including passive sensing. Submissions should prioritize interpretable reasoning (concept-based, prototype, counterfactual, causal), calibrated uncertainty, fairness and bias assessment, robustness to domain shift, and reporting that enables reproducibility and external validation. We particularly welcome multi-site studies, federated or privacy-preserving learning, human-in-the-loop AI-methodologies, and real-world deployments that demonstrate clinical utility. Reviews, benchmarks, negative/neutral results with rigorous error analysis, and open datasets/tools that accelerate translation are also encouraged.

Dr. Gianluca Amprimo
Dr. Claudia Ferraris
Dr. Andreas Miltiadous
Guest Editors

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Keywords

  • explainability
  • AI
  • digital biomarkers
  • telemedicine
  • medical imaging
  • biosignals
  • neurodegenerative disorders
  • personalized medicine
  • disease diagnosis and monitoring

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Published Papers

This special issue is now open for submission.
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