Innovations in Kidney Disease Diagnostics: Organoids, Pathology, and Clinical Insights

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 30 November 2026

Special Issue Editor


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Guest Editor
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Interests: renal development; kidney fibrosis; acute kidney injury; chronic kidney disease; regeneration; dialysis
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Special Issue Information

Dear Colleagues,

The field of kidney disease diagnostics is undergoing rapid transformation driven by advances in experimental models, tissue analysis, biomarker discovery, and computational technologies. Kidney organoids derived from pluripotent cells have enabled high-resolution assessment of tubular injury, nephrotoxicity, and disease-related phenotypes. In addition, innovations in renal pathology, including digital pathology, multiplex immunostaining, and spatial transcriptomics, provide unprecedented detail on tissue structure and molecular alterations. Moreover, the progress in clinical diagnostics, such as novel urinary and blood biomarkers, omics-based profiling, machine learning-driven data interpretation, and quantitative imaging methodologies, is expanding the toolbox for early detection, risk stratification, and mechanistic classification of kidney disorders.

This Special Issue, “Innovations in Kidney Disease Diagnostics: Organoids, Pathology, and Clinical Insights,” aims to cover diverse methodological advances that contribute to a deeper and more integrated understanding of kidney disease. We welcome studies involving organoid-based assays, pathological diagnostics, biomarker development, clinical laboratory innovations, computational or AI-assisted diagnostic approaches, multi-omics analyses, and new conceptual or technological frameworks for improving kidney disease diagnostics.

Dr. Kenji Tsuji
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic kidney disease
  • diabetic kidney disease
  • glomerulonephritis
  • polycystic kidney diseases
  • renal pathology
  • biomarker
  • kidney regeneration
  • hemodialysis
  • peritoneal dialysis
  • diagnosis

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Published Papers

This special issue is now open for submission.
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