Diagnosis, Prophylaxis and Treatments of Cytomegalovirus Infection and Reactivation
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 3782
Special Issue Editor
Interests: hematopoietic stem cell transplantation; haploidentical HSCT; advanced cell therapies; inherited bone marrow failure syndromes; immunodeficiency/immune regulatory disorders; high-risk neuroblastoma
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to our Special Issue “Diagnosis, Prophylaxis and Treatments of Cytomegalovirus Infection and Reactivation”.
Cytomegalovirus (CMV) is a well-known ubiquitous herpesvirus that is highly diffused among the population with an estimated overall seroprevalence rate of over 50% that increases with age.
It is known to cause a wide range of clinical syndromes, from asymptomatic infection in most healthy hosts to severe and even fatal disease in newborns and immunocompromised individuals. Among these, hematopoietic stem cell transplantation (HSCT) recipients are the population at higher risk, in which CMV reactivation represents one of the most frequent viral complications, occurring in about 70% of CMV seropositive HSCT recipients, with rates of recurrence after a first CMV-DNAemia as high as 50–70%.
Despite the development of diagnostic approaches, with prophylaxis and pre-emptive therapy in patients at risk having contributed over the years to improved outcomes of CMV infection or reactivation, the management of CMV remains challenging.
In this Special Issue, we aim to explore current and innovative diagnostic approaches and treatment strategies whose understanding and improvement is crucial in the management and prevention of CMV-related complications.
We look forward to receiving your contributions.
Dr. Stefano Giardino
Guest Editor
Manuscript Submission Information
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Keywords
- cytomegalovirus (CMV)
- diagnosis
- laboratory techniques
- molecular methods
- new antiviral drugs
- antiviral cell therapy
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