Organ-Specific PET in Diagnostics

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 November 2024) | Viewed by 1530

Special Issue Editor


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Guest Editor
Fujita Medical Innovation Center Tokyo, Fujita Health University, Haneda Clinic, Tokyo, Japan
Interests: PET; organ-specific; diagnostic imaging

Special Issue Information

Dear Colleagues,

Whole-body PET/CT has become one of the most important diagnostic imaging modalities in oncology because its image quality has dramatically improved in recent years due to advances in detectors and image reconstruction methods. However, since the distance between the PET detector and the subject must be reduced to achieve even higher resolution, whole-body PET/CT has limited diagnostic capability for localized depth of cancer, while it is excellent for the diagnosis of metastases.

In recent years, organ-specific PET systems have been developed that are smaller than whole-body PET/CT systems. These PET scanners are designed for specific organs and have the advantages of (i) detecting smaller lesions with higher accuracy and (ii) visualizing better the minute contrast between normal and abnormal areas, which is difficult to achieve with whole-body PET/CT. Breast-specific PET was the first PET scanner to be clinically available, followed by brain-specific PET. Several other novel organ-specific PET scanners are also in development.

This Special Issue aims to provide the latest findings on these systems for the further development of organ-specific PET and its contribution to patient care.

Dr. Yoko Satoh
Guest Editor

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Published Papers (1 paper)

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Research

9 pages, 2033 KiB  
Article
Can the Newer Model of Breast-Specific Positron Emission Tomography Reduce the “Blind Area”?
by Yoko Satoh, Jiro Ishida, Yoshitaka Inui, Akinori Takenaka, Shuji Bando, Sayuri Ishida and Hiroshi Toyama
Diagnostics 2024, 14(18), 2068; https://doi.org/10.3390/diagnostics14182068 - 19 Sep 2024
Viewed by 975
Abstract
Objectives: Breast-specific positron emission tomography (PET) provides higher sensitivity and spatial resolution than whole-body PET/CT, but it has a blind area. Mammary glands near the chest wall sometimes present outside the field of view (FOV). A newer, dedicated breast PET (dbPET) model [...] Read more.
Objectives: Breast-specific positron emission tomography (PET) provides higher sensitivity and spatial resolution than whole-body PET/CT, but it has a blind area. Mammary glands near the chest wall sometimes present outside the field of view (FOV). A newer, dedicated breast PET (dbPET) model has a cylindrical detector with a larger diameter than previous models, so it is expected to eliminate or reduce blind areas. This study aimed to compare breast images acquired on the new dbPET model with images acquired on an older dbPET model to evaluate blind area reduction. Methods: The nipple-to-chest wall distance (mm), maximum breast cross-sectional area at the FOV edge (cm2) on the dbPET transverse images of the scanners, and the effects of patient age and body mass index (BMI) were compared. Results: There was no significant difference in the nipple-to-chest wall distance between the models (p = 0.223). The maximum breast cross-sectional area at the FOV edge was significantly larger on the newer model’s images (p < 0.001). There was no significant correlation between breast size and the rate of change in both parameters. Conclusions: The new ring-type dbPET scanners with larger diameter detectors did not reduce the blind area observed on older dbPET scanners. Full article
(This article belongs to the Special Issue Organ-Specific PET in Diagnostics)
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