Diagnostic and Interventional Radiology of Liver Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 1576

Special Issue Editors


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Guest Editor
Department of Diagnostic and Interventional Radiology, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany
Interests: diagnostic radiology; interventional radiology; magnetic resonance imaging; computed tomography; contrast agents; artificial intelligence; hepatobiliary imaging; hepatocellular carcinoma; defuse liver disease; minimal invasive therapy
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Guest Editor
Department of Radiology and Nuclear Medicine, Städtisches Klinikum Braunschweig, Brunswick, Germany
Interests: diagnostic radiology; computed tomography; hepatocellular carcinoma; magnetic resonance; ultrasonography liver diseases; medical imaging

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Guest Editor
Department of Diagnostic and Interventional Radiology, Hospital Wuerzburg Mitte, 97074 Wuerzburg, Germany
Interests: liver diseases; cirrhosis; liver cirrhosis; hepatocellular carcinoma; radiofrequency ablation; fibrosis; RFA; liver failure; NASH

Special Issue Information

Dear Colleagues,

This Special Issue is dedicated to the in-depth analysis of the latest diagnostic and interventional radiology advancements, focusing on treating liver diseases. In this Special Issue, we seek diverse articles, including pioneering research findings and detailed clinical case studies. We aim to deepen the understanding of this vital medical field and highlight radiology's dynamic and evolving role in liver diseases.

We are interested in submissions exploring advancements in imaging modalities, like MRI, CT scans, and ultrasound. These technologies are crucial in accurately diagnosing various liver conditions and are pivotal in early detection, significantly impacting patients’ treatment plans. 

A significant portion is devoted to the latest minimally invasive techniques. Contributions detailing procedures, like transarterial chemoembolization (TACE), radiofrequency ablation (RFA), and other innovative interventional methods, are highly encouraged. We also emphasize the role of artificial intelligence and cutting-edge imaging in enhancing the precision and effectiveness of both diagnostic and interventional procedures. Submissions that explore integrating these technologies in clinical practice, offering new perspectives on patient management and treatment strategies, are highly encouraged.

Who Should Contribute?

This Special Issue will assist many medical professionals, including radiologists, interventionalists, and hepatologists. We aim to bridge the gaps between different specialties and foster an integrated approach to liver disease management. In line with our commitment to broad knowledge dissemination, all the papers in this Special Issue will be fully open access upon publication after a thorough peer-review process. 

Prof. Dr. Niklas Verloh
Prof. Dr. Philipp Wiggermann
Prof. Dr. Michael Haimerl
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • interventional radiology
  • MRI
  • CT scans
  • early detection
  • ultrasound
  • liver diseases
  • transarterial chemoembolization (TACE)
  • radiofrequency ablation (RFA)
  • artificial intelligence
  • cutting-edge imaging
  • clinical practice

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Published Papers (1 paper)

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Research

10 pages, 2354 KiB  
Article
Differentiating Well-Differentiated from Poorly-Differentiated HCC: The Potential and the Limitation of Gd-EOB-DTPA in the Presence of Liver Cirrhosis
by Andrea Goetz, Niklas Verloh, Kirsten Utpatel, Claudia Fellner, Janine Rennert, Ingo Einspieler, Michael Doppler, Lukas Luerken, Leona S. Alizadeh, Wibke Uller, Christian Stroszczynski and Michael Haimerl
Diagnostics 2024, 14(15), 1676; https://doi.org/10.3390/diagnostics14151676 - 2 Aug 2024
Viewed by 1197
Abstract
This study uses magnetic resonance imaging (MRI) to investigate the potential of the hepatospecific contrast agent gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) in distinguishing G1- from G2/G3-differentiated hepatocellular carcinoma (HCC). Our approach involved analyzing the dynamic behavior of the contrast agent in different phases of [...] Read more.
This study uses magnetic resonance imaging (MRI) to investigate the potential of the hepatospecific contrast agent gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) in distinguishing G1- from G2/G3-differentiated hepatocellular carcinoma (HCC). Our approach involved analyzing the dynamic behavior of the contrast agent in different phases of imaging by signal intensity (SI) and lesion contrast (C), to surrounding liver parenchyma, and comparing it across distinct groups of patients differentiated based on the histopathological grading of their HCC lesions and the presence of liver cirrhosis. Our results highlighted a significant contrast between well- and poorly-differentiated lesions regarding the lesion contrast in the arterial and late arterial phases. Furthermore, the hepatobiliary phase showed limited diagnostic value in cirrhotic liver parenchyma due to altered pharmacokinetics. Ultimately, our findings underscore the potential of Gd-EOB-DTPA-enhanced MRI as a tool for improving preoperative diagnosis and treatment selection for HCC while emphasizing the need for continued research to overcome the diagnostic complexities posed by the disease. Full article
(This article belongs to the Special Issue Diagnostic and Interventional Radiology of Liver Diseases)
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