Biomarkers, Pathology and Diagnosis of Breast Cancer

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1015

Special Issue Editor


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Guest Editor
Department of Biology, Georgia State University, Atlanta, GA 30303, USA
Interests: breast cancer; cancer biology; biomarkers

Special Issue Information

Dear Colleagues,

In women, breast cancer is the most frequently diagnosed cancer and ranks second among the causes of cancer-related death. However, men can also get this type of cancer.

Common types of breast cancer include invasive (infiltrating) ductal carcinoma (IDC), lobular breast cancer, and ductal carcinoma in situ (DCIS). 

There are various ways of identifying and confirming the presence of breast cancer, including clinical examination, mammography, ultrasound, magnetic resonance imaging (MRI), positron emission tomography (PET) scanning, and other diagnostic techniques.

This Special Issue aims to encourage high-quality original articles and reviews that can provide better insights into the current knowledge regarding the biomarkers, pathology, and diagnosis of breast cancer.

Dr. Karuna Mittal
Guest Editor

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Keywords

  • breast cancer
  • breast ductal carcinoma in situ
  • biomarkers
  • radiation therapy
  • prognostic significance

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Published Papers (1 paper)

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9 pages, 2715 KiB  
Case Report
Synchronous Primary Metastatic Infra-Mammary Accessory Breast Cancer and Ipsilateral Breast Cancer: An Extremely Rare Case Report
by Marius Preda, Nilima Rajpal Kundnani, Roxana Buzas, Sorin Dema, Adrian Carabineanu, Codruta Dana Miclaus, Razvan Ilina, Octavian Marius Cretu and Alexandru Blidisel
Diagnostics 2024, 14(23), 2699; https://doi.org/10.3390/diagnostics14232699 - 29 Nov 2024
Viewed by 709
Abstract
Background: Accessory breast cancer cases are rarely reported in the literature. Of the reported cases, the predominantly available ones are those localized in the axillary region. Methods: We present here a very rare case of metastatic accessory breast cancer. It was located in [...] Read more.
Background: Accessory breast cancer cases are rarely reported in the literature. Of the reported cases, the predominantly available ones are those localized in the axillary region. Methods: We present here a very rare case of metastatic accessory breast cancer. It was located in the infra-mammary region (IMR). IMR accessory breast cancer is a rare form of breast cancer. Although ectopic nipples are occasionally found in the IMR, because of the lack of ductal tissue malignant changes, they are rare. Results: In our case, the primary tumor was localized in the congenital accessory breast tissue (ABT). It was recognized as invasive lobular accessory breast cancer cT3N1M0 with a second NST carcinoma, cT2N0M0, Stage IIA, in the ipsilateral breast. A multi-modal approach was applied. Adjuvant chemotherapy was carried out with epirubicin, cyclophosphamide, and paclitaxel, with post-chemotherapy ultrasound followed by right radical mastectomy. Adjuvant radiotherapy was given to our patient in the form of 25 fractions of 50 GY for 25 days, followed by hormonal treatment with Letrozole, 2.5 mg/day, to be continued for 5 years. Conclusions: our case demonstrates that since it is rare to find accessory breast cancer in the infra-mammary region, early identification and management with a multi-modal approach can lead to a successful patient outcome. Full article
(This article belongs to the Special Issue Biomarkers, Pathology and Diagnosis of Breast Cancer)
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