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Diagnostics
Special Issues
Novel Diagnostic Approaches and Personalized Interventions for Sleep Disorders
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Novel Diagnostic Approaches and Personalized Interventions for Sleep Disorders

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 356

Special Issue Editors

Prof. Dr. Dagmara Dimitriou

E-Mail Website
Guest Editor
Sleep Education and Research Laboratory, UCL Institute of Education, University College London, London, UK
Interests: sleep; neurodevelopmental disorders; mental health; medical conditions, actigraphy
Dr. Zaid Awad

E-Mail Website
Guest Editor
1. Department of Otolaryngology, Imperial College Healthcare NHS Trust, London W6 8RF, UK
2. Department of Surgery and Cancer, Imperial College, London SW7 2AZ, UK
Interests: otolaryngology; sleep; voice disorders; hearing and balance
Special Issues, Collections and Topics in MDPI journals
Dr. Mustafa Jaafar

E-Mail Website
Guest Editor Assistant
UCL Artificial Intelligence Centre for Doctoral Training, University College London, London WC1H 0AA, UK
Interests: ENT surgery; machine learning; cybersecurity; blockchain

Special Issue Information

Dear Colleagues,

Sleep is a fundamental physiological process essential for healthy cognitive, emotional, and physical functioning throughout life. However, sleep health is influenced by a complex interaction of biological, cultural, environmental, and social factors, which can vary significantly across populations and settings.

Despite growing awareness, sleep disorders including insomnia, circadian rhythm disturbances, and especially obstructive sleep apnoea (OSA) remain widely underdiagnosed and undertreated in both children and adults worldwide.

Diagnosing and managing sleep disorders presents ongoing challenges, particularly when they co-occur with neurodevelopmental conditions such as autism spectrum disorder (ASD) and ADHD, or with chronic medical illnesses. Factors such as cultural beliefs, disparities in healthcare access, and inconsistent diagnostic criteria further complicate timely and accurate assessment and intervention.

We are pleased to invite submissions to this Special Issue of Diagnostics, which aims to showcase recent advances in individualised approaches to sleep assessment and intervention. Particular focus will be given to OSA and other prevalent sleep conditions across diverse clinical and cultural settings.

This Special Issue will highlight innovative diagnosis and assessment methods across clinical, psychological, and biomedical disciplines and explore novel therapeutic strategies. We also encourage research that considers the social, cultural, and biological factors shaping sleep health.

Prof. Dr. Dagmara Dimitriou
Dr. Zaid Awad
Guest Editors

Dr. Mustafa Jaafar
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sleep disorders
  • obstructive sleep apnoea
  • diagnosis
  • personalized treatment
  • neurodivergence
  • comorbidities
  • cross-cultural sleep
  • wearable technology
  • paediatric sleep
  • public health

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

14 pages, 1493 KB  
Article
Discrepancies in Subjective Sleep Quality Between Home and Hospital Settings: Insights of Hypnotic Agents Use with Post-Polysomnography Questionnaire
by Jing-Jie Wang and Ming-Feng Wu
Diagnostics 2025, 15(24), 3153; https://doi.org/10.3390/diagnostics15243153 - 11 Dec 2025
Viewed by 215
Abstract
Background/Objectives: Polysomnography (PSG) is the gold standard for diagnosing sleep-disordered breathing (SDB). However, in a hospital testing setting, it may produce the first-night effect, viz., prolonged sleep latency, lower sleep efficiency, and uncertain apnea–hypopnea index (AHI). Here, we aim to determine the influences [...] Read more.
Background/Objectives: Polysomnography (PSG) is the gold standard for diagnosing sleep-disordered breathing (SDB). However, in a hospital testing setting, it may produce the first-night effect, viz., prolonged sleep latency, lower sleep efficiency, and uncertain apnea–hypopnea index (AHI). Here, we aim to determine the influences of hypnotic agents and gender. Methods: In this retrospective study, we reviewed the post-PSG questionnaires and electronic medical records of patients aged ≥20 years receiving overnight PSG for the diagnosis of SDB at Taichung Veterans General Hospital in a period between April 2024 and March 2025. Results: We studied a total of 1053 patients, aged 47.0 ± 14.7 years old. Compared to sleeping at home, 42.2% of patients reported worse perceived sleep quality (PSQ) with hypnotic agents, and 53.0%, without, before PSG testing in the hospital. For those without taking hypnotic agents, men had an odds ratio (OR) of 1.570 (95% CI: 1.127–2.189) for worsening PSQ compared to women (p = 0.008). Also, per increasing 1 Epworth Sleepiness Scale (ESS) score, the risk of worsening PSQ was reduced by OR of 0.963 (95% CI: 0.933–0.994) (p = 0.021). Once male patients had ESS < 10, as many as 57.3% of them reported the worse PSQ. Conclusions: Our study suggests a potentially more patient-centric approach to diagnosing sleep-disordered breathing. In some male patients with ESS scores < 10, short-acting hypnotics might be considered during in-lab PSG to improve subjective comfort, thereby potentially enhancing study reliability. Meanwhile, home sleep apnea testing can serve as a practical initial tool for selected patients—offering convenience, mitigating the first-night effect, and potentially reducing long wait times. However, its use in individuals with comorbid insomnia requires careful clinical judgment to avoid false-negative results, often making in-lab assessment the preferred option in such cases. Full article
(This article belongs to the Special Issue Novel Diagnostic Approaches and Personalized Interventions for Sleep Disorders)
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