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Journals
Dermatopathology
Special Issues
Educational Case Reports in Dermatopathology
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Educational Case Reports in Dermatopathology

A special issue of Dermatopathology (ISSN 2296-3529).

Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 7992

Special Issue Editor

Prof. Dr. Gürkan Kaya

E-Mail Website
Guest Editor
1. Department of Dermatology, University Hospital of Geneva, 1205 Geneva, Switzerland
2. Department of Clinical Pathology, University Hospital of Geneva, 1205 Geneva, Switzerland
Interests: molecular pathology of skin aging and dermatoporosis; clinicopathological correlation in inflammatory dermatoses; pathology of melanocytic lesions; molecular dermatopathology; dermatotoxicopathology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Dermatopathology is an international, peer-reviewed, open access journal published quarterly online by MDPI. Dermatopathology runs Special Issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and directions of research. Guest Editors who are experts in the subject and oversee the editorial process for papers lead Special Issues.

Now we start a new initiative—we aim to collect and publish case reports as teaching tools in dermatopathology. With this in mind, we would like to dedicate this Special Issue to the discussion of teaching cases in dermatopathology. We would like to share experience: if a case has challenged us, it will probably challenge and intrigue others, and reading about it may give a clue, or at least a hint, for a better understanding.

Please send us your latest case report highlighting the main message and the difficulties you experienced on the way to diagnosis and/or in their management.

Prof. Dr. Gürkan Kaya
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dermatopathology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

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5 pages, 1695 KiB  
Case Report
Intratarsal Keratinous Cyst Clinically Misdiagnosed as a Chalazion
by John Lennon Silva Cunha, Clenia E. S. Andrade, Fernando A. P. da Cunha Filho, Alexandre R. da Paz, Manuel A. Gordón-Núñez, Pollianna M. Alves and Cassiano F. W. Nonaka
Dermatopathology 2024, 11(2), 142-146; https://doi.org/10.3390/dermatopathology11020014 - 19 Apr 2024
Viewed by 1517
Abstract
The intratarsal keratinous cyst (IKC) is a recently described entity, often clinically misdiagnosed as a chalazion. We report a case of a 61-year-old male patient with a chief complaint of a small lesion on the upper eyelid that evolved over six months. On [...] Read more.
The intratarsal keratinous cyst (IKC) is a recently described entity, often clinically misdiagnosed as a chalazion. We report a case of a 61-year-old male patient with a chief complaint of a small lesion on the upper eyelid that evolved over six months. On physical examination, an asymptomatic, firm nodule was identified on the left upper eyelid. The patient reported no history of trauma. A provisional diagnosis of chalazion was established, and an excisional biopsy was performed. Histopathologically, the lesion was lined with a stratified squamous epithelium, with a corrugated epithelial surface showing abrupt keratinization without keratohyalin granules, and compact keratinous-appearing material in the cystic lumen. The diagnosis was IKC. No signs of recurrence were observed after one year of follow-up. It is essential to accurately diagnose IKC and distinguish it from chalazion and epidermal inclusion cysts, because IKC requires complete surgical excision and can exhibit multiple recurrences if not properly removed. Full article
(This article belongs to the Special Issue Educational Case Reports in Dermatopathology)
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6 pages, 7811 KiB  
Case Report
A Case of Pleomorphic Dermal Sarcoma: Giant Exophytic Tumor of the Medial Canthus
by Rylee Moody, Kavita Darji, Tricia A. Missall, Peter Chow and Ramona Behshad
Dermatopathology 2024, 11(1), 13-18; https://doi.org/10.3390/dermatopathology11010003 - 29 Dec 2023
Viewed by 1742
Abstract
We present the case of a 99-year-old Caucasian female who was referred for treatment of a painless, 8.0 cm × 7.8 cm exophytic, pedunculated, ulcerated tumor of the left medial canthus. Pathology showed spindled, oval, and polygonal cells with pleomorphic nuclei. Many multinuclear [...] Read more.
We present the case of a 99-year-old Caucasian female who was referred for treatment of a painless, 8.0 cm × 7.8 cm exophytic, pedunculated, ulcerated tumor of the left medial canthus. Pathology showed spindled, oval, and polygonal cells with pleomorphic nuclei. Many multinuclear giant cells and mitotic figures were also noted. The tumor was highlighted with CD10, showed focal positivity with actin, desmin, and CD68, and had increased Ki67 immunohistochemical staining. The tumor was negative for pancytokeratin, CK5/6, p63, MART-1/MelanA, S100, Sox10, p40, CD34, and CD23. Based on clinicopathologic correlation, the diagnosis of pleomorphic dermal sarcoma (PDS) was made. Pleomorphic dermal sarcoma (PDS) refers to a deep, histologically high-grade tumor that often resembles other tumors clinically and histologically. As PDS is frequently aggressive and related to adverse outcomes, it is important to recognize its distinguishing features in comparison to other similar entities, including atypical fibroxanthoma (AFX) and pleomorphic leiomyosarcoma (PLMS). To our knowledge, there is only one other reported case in the literature of PDS occurring on the eye. By reviewing and understanding characteristic etiologies, locations of presentation, histopathological features, and management techniques, pathologists can make a more accurate diagnosis and dermatologists can provide more effective patient care in a timely manner. Full article
(This article belongs to the Special Issue Educational Case Reports in Dermatopathology)
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8 pages, 1922 KiB  
Case Report
Dermatomyositis with Eosinophils
by Isabella I. Sanchez, Henry O. Herrera, Ashley Elsensohn, Bonnie A. Lee and Christina N. Kraus
Dermatopathology 2023, 10(4), 310-317; https://doi.org/10.3390/dermatopathology10040039 - 21 Nov 2023
Viewed by 3190
Abstract
Dermatomyositis is an idiopathic inflammatory myopathy that often presents with symmetric proximal skeletal muscle weakness and characteristic skin findings. Typical skin biopsy findings include vacuolar changes of the basal layer, increased dermal mucin, and a predominantly lymphocytic infiltrate. We report a case of [...] Read more.
Dermatomyositis is an idiopathic inflammatory myopathy that often presents with symmetric proximal skeletal muscle weakness and characteristic skin findings. Typical skin biopsy findings include vacuolar changes of the basal layer, increased dermal mucin, and a predominantly lymphocytic infiltrate. We report a case of dermatomyositis presenting as intensely pruritic papules and plaques, with initial histopathology being atypical of dermatomyositis due to the presence of eosinophils. The initial biopsy demonstrated a superficial dermatitis with eosinophils, initially thought to represent a drug eruption. A second biopsy of the same cutaneous manifestation was performed at a later time given high clinical suspicion for dermatomyositis and demonstrated a more classic vacuolar interface dermatitis with increased mucin and an absence of eosinophils. Notably, increased pruritus was specifically associated with the lesion that demonstrated tissue eosinophilia. The case illustrates the importance of considering tissue eosinophilia in the histologic presentation of dermatomyositis. Full article
(This article belongs to the Special Issue Educational Case Reports in Dermatopathology)
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