Advanced Research on Oral Cancer and Dental Implants: 2nd Edition

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: 30 September 2026 | Viewed by 591

Editors


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Guest Editor
1. ICE Postgraduate Dental Institute and Hospital, Salford M50 3XZ, UK
2. School of Health and Society, University of Salford, Salford M5 4WT, UK
3. Department of Health and Medicine, Lancaster Medical School, University of Lancaster, Lancaster LA1 4YW, UK
Interests: oral medicine; oral cancer; dental implants; digital dentistry; diabetes mellitus; salivary molecules; biomaterials; translational research
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Guest Editor
Department of Radiography, School of Health and Society, University of Salford, Salford M5 4WT, UK
Interests: observer performance studies; receiver operating characteristic analysis; medical imaging
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. ICE Postgraduate Dental Institute and Hospital, Salford M50 3XZ, UK
2. School of Health and Society, University of Salford, Salford M5 4WT, UK
Interests: human factors; dental implants; bone regeneration; sinus lifting; digital dentistry; oral and maxillofacial surgery
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. ICE Postgraduate Dental Institute and Hospital, Salford M50 3XZ, UK
2. School of Health and Society, University of Salford, Salford M5 4WT, UK
Interests: dental implants; sinus lifting; zygomatic implants; bone regeneration; full mouth rehabilitation; reconstructive jaw surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Oral cancer is the eighth most frequent cancer worldwide, with a 5% survival rate of 50%, and oral cancer is sometimes in advanced stages at the time of diagnosis. Oral squamous cell carcinoma accounts for 90% of oral cavity cancers. It is an invasive cancer, and it can spread to other parts of body. The gold standard methods for diagnosing oral cancer are also invasive, costly, time consuming, and technique-sensitive.

Dental implants are known to be the optimal treatment option for partially or fully edentulous patients. There are several risk factors associated with dental implant failure that may lead to early implant loss and that may decrease the quality of life of the patient. Therefore, it is important to understand the optimization of the procedures and how to improve the survival of dental implants and their placement. New knowledge on how to support oral cancer patients and the role of implant dentistry is still needed to develop an evidence-based approach to overcome the challenges of robust knowledge in implant dentistry.

Advances in oral cancer research are required to provide new information about non-invasive screening and diagnostic methods, cellular processes and molecular biology, chemical pathways, and the pathogenesis of cancer for the identification of biological markers and molecular-targeted therapies. Along with the evaluation of the survival of dental implants in patients who are affected by oral cancer, the timing of implant placement and anatomy site as well as the treatment dosage that are relevant to understanding implant effectiveness.

This Special Issue invites research and studies on oral cancer and implant dentistry, especially those paying particular attention to translational research and clinical trials as well as high-quality review papers that will lead to an improved understanding of oral cancer and implant dentistry as well as novel methods and techniques for the prevention, diagnosis, treatment, and improved prognosis of patients.

Prof. Dr. Rabia Sannam Khan
Dr. John D. Thompson
Prof. Simon Wright
Prof. Dr. Cemal Ucer
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck cancer
  • oral squamous cell carcinoma
  • dental implants
  • oral surgery
  • tissue regeneration
  • peri-implantitis
  • oral rehabilitation
  • translational oral cancer research
  • biomarkers
  • molecular analysis and chemical pathways
  • non-invasive diagnostic methods
  • minimally invasive techniques
  • CAD/CAM prosthetics

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Published Papers (1 paper)

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18 pages, 14094 KB  
Article
Descriptive CBCT Findings of Maxillary Sinus Mucosal Changes in Patients Undergoing Sinus Floor Elevation: A Retrospective Observational Study
by Nicole Mckeever, Rabia Khan, Cemal Ucer, Simon Wright and Adam Spacey
Dent. J. 2026, 14(6), 340; https://doi.org/10.3390/dj14060340 - 2 Jun 2026
Viewed by 337
Abstract
Objectives: To assess the prevalence of maxillary sinus pathology in patients requiring sinus floor elevation to aid dental implant treatment. The study aimed to identify the degree, morphology, and location of mucosal thickening and its relation to ostium patency, as well as any [...] Read more.
Objectives: To assess the prevalence of maxillary sinus pathology in patients requiring sinus floor elevation to aid dental implant treatment. The study aimed to identify the degree, morphology, and location of mucosal thickening and its relation to ostium patency, as well as any odontogenic pathology contributing to mucosal thickening. Methods: This study was conducted at the ICE Postgraduate Dental Institute and Hospital, England, UK, between February and April 2025. cone-beam computed tomography (CBCT) scans of 20 patients who were partially dentate and edentulous who attended ICE for sinus floor elevation (SFE) between August 2023 and March 2025 were retrospectively examined. Mucosal thickening >2 mm was considered pathological. The CBCT scans of 26 maxillary sinuses were analysed for the following mucosal thickening characteristics: degree, morphology, and location of mucosal thickening, ostium patency, presence of odontogenic pathology, and need for onward referral to otorhinolaryngology. Data was also collected in relation to patient demographics and CBCT parameters. Descriptive statistics were used to summarise the data. Results: Of the 26 sinuses examined in the study, 69% presented with mucosal thickening greater than 2 mm. The incidence of mucosal thickening was higher in male patients. Polypoid mucosal thickening was the most common morphology observed in 46%, and circumferential thickening was the most common location observed in 50%. Ostium obstruction was seen in 12.5% of sinuses that had polypoid, circumferential thickening >10 mm. Other incidental findings included apical pathology, periodontal disease, dental implants breaching the sinus floor, and an antrolith. Conclusions: The study found a high incidence of mucosal thickening in patients undergoing sinus floor elevation. The degree and morphology of mucosal thickening, along with ostium patency and the presence of odontogenic pathology, are important factors to consider in preoperative assessment. Large field of view CBCT scans are required to allow visualisation of the osteomeatal complex. Collaboration between dental implantologists and otorhinolaryngologists is crucial for managing patients with sinus pathology and ensuring successful outcomes in SFE. Further larger prospective studies with clinical correlation are needed to better evaluate the association between sinus pathology, ostium patency, and sinus floor elevation outcomes. Full article
(This article belongs to the Special Issue Advanced Research on Oral Cancer and Dental Implants: 2nd Edition)
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