Protein Crystallography: The State of the Art

Dear Colleagues,

X-ray diffraction is a prime technique to reveal the three-dimensional structures of biological molecules (proteins, metallo-enzymes, viruses and nucleic acids) at an atomic resolution of ~1.3 Å. Static structural information has been used to reveal the detailed mechanisms through which these molecules carry out their functions. Recent technical developments have made it possible to observe the structural dynamics of macromolecules and their complexes using various diffraction techniques available in third- or fourth-generation synchrotron sources.

We invite researchers to contribute to this Special Issue on “Protein Crystallography: the State of the Art”, which is intended to serve as a unique forum covering broad aspects of the current status of time-resolved serial crystallography in XFEL and in synchrotrons, pink beam crystallography and its progress and prospects in the field of mechanistic enzymology, structural-based drug discovery, an understanding of macromolecular complexes and membrane proteins as well as future software developments for macromolecular crystallography, and crystallization and complementary techniques (i.e., SAXS, NMR, spectroscopic techniques). We accept research articles, reviews and short communications.

Dr. Vasundara Srinivasan
Dr. Santosh Panjikar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.