Cardiovascular Disease in Children: From Neonatal Hemodynamics to Early Vascular Aging
A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Cardiology".
Deadline for manuscript submissions: 25 August 2026 | Viewed by 135
Special Issue Editors
Interests: pediatric cardiology; fetal and pediatric echocardiography; risk factors for adult onset cardiovascular disease; epidemiology of congenital heart disease; pulmonary hypertension
Special Issue Information
Dear Colleagues,
Cardiovascular disease (CVD) is increasingly recognized as a life-course condition, with potential origins in fetal life, the neonatal period, and early childhood. Subclinical cardiovascular alterations—including myocardial dysfunction, vascular stiffness, and early cardiac remodeling—can be detected decades before overt disease becomes apparent. Identifying these early changes offers a critical opportunity for prevention.
This Special Issue of Children will explore cardiovascular disease across the pediatric spectrum, from neonatal hemodynamic adaptation to early vascular aging in adolescents. In neonates—particularly moderate- and late-preterm infants—optimizing fluid management and circulatory support remains a key challenge. Functional echocardiography and targeted neonatal cardiac assessment are transforming bedside decision-making, yet evidence-based strategies continue to evolve.
Beyond the neonatal period, infectious and inflammatory conditions—including viral myocarditis and sepsis—may impair myocardial function, sometimes with lasting consequences. Meanwhile, metabolic disorders are increasingly associated with early endothelial dysfunction, arterial stiffness, and adverse cardiac remodeling.
We welcome original research, reviews, and meta-analyses addressing early cardiovascular phenotyping, advanced imaging, vascular biomarkers, metabolic risk, and prevention strategies in children. By integrating neonatal physiology, infection-related cardiac injury, and cardiometabolic disease, this Special Issue aims to advance the understanding of early cardiovascular risk and inform strategies to reduce the global burden of CVD beginning in childhood.
Prof. Dr. Ageliki A. Karatza
Dr. Marietta Charakida
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cardiovascular disease in children
- early cardiovascular risk
- paediatric cardiology
- neonatal haemodynamics
- functional echocardiography
- preterm infants
- myocardial dysfunction
- arterial stiffness
- vascular aging
- endothelial dysfunction
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