Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
3.8
2.1
Journals
Children
Special Issues
Future Directions in Pediatric Perioperative Care: Enhanced Recovery, Regional Analgesia...
share announcement

Future Directions in Pediatric Perioperative Care: Enhanced Recovery, Regional Analgesia and Personalized Medicine

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Anesthesiology, Pain Medicine and Palliative Care".

Deadline for manuscript submissions: closed (10 May 2025) | Viewed by 608

Special Issue Editors

Dr. Megan Brockel

E-Mail Website
Guest Editor
Department of Anesthesiology, Section of Pediatric Anesthesiology, Children's Hospital Colorado, 13123 East 16th Avenue, B090, Aurora, CO 80045, USA
Interests: anesthesiology
Dr. Robert Moore

E-Mail Website
Guest Editor
Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY, USA
Interests: the quality of recovery after pediatric surgery; regional analgesia; pain management; enhanced recovery after pediatric surgery; the validation and application of tools to measure the quality of pediatric recovery
Dr. Kyle O. Rove

E-Mail Website
Guest Editor
Department of Pediatric Urology, Children's Hospital Colorado, Aurora, CO, USA
Interests: Enhanced Recovery After Surgery (ERAS) in infants; children and young adults undergoing urologic surgery

Special Issue Information

Dear Colleagues,

New concepts and approaches to care are impacting both the understanding and quality of pediatric perioperative medicine. These efforts could allow physicians to address numerous concerns including issues related to health equity and the perioperative workforce. Ultimately, understanding the impact of these changes can be a springboard for improvement and may even help facilitate a transition to personalized medicine.

Enhanced recovery after pediatric surgery, evolving approaches to regional analgesia and efforts to quantify the quality of recovery following pediatric surgery exemplify these innovative approaches to pediatric perioperative care and will be the focus of this Special Issue.

We welcome original investigations, meta-analyses, narrative reviews and commentaries for submission to this Special Issue. 

Thank you in advance for your consideration.

Dr. Megan Brockel
Dr. Robert Moore
Dr. Kyle O. Rove
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • enhanced recovery
  • pain management
  • regional analgesia
  • quality of recovery
  • pediatric surgery
  • neonatal surgery
  • pediatric anesthesia

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

12 pages, 537 KiB  
Article
Intraoperative Methadone Versus Non-Methadone Analgesia in Pediatric Cardiac Surgery: A Retrospective Cohort Study
by Brian Blasiole, Danielle R. Lavage, Hsing-Hua Sylvia Lin, Scott E. Licata, Sahana Sivam, Inesh Sivam, Laura M. Le and Senthilkumar Sadhasivam
Children 2025, 12(5), 567; https://doi.org/10.3390/children12050567 - 28 Apr 2025
Viewed by 370
Abstract
Introduction: Methadone is an opioid-sparing opioid and it is increasingly used in children undergoing surgery due to its beneficial effects on postoperative pain scores, decreased opioid requirements, and fewer adverse effects compared to other opioids. Intraoperative methadone is not well studied in pediatric [...] Read more.
Introduction: Methadone is an opioid-sparing opioid and it is increasingly used in children undergoing surgery due to its beneficial effects on postoperative pain scores, decreased opioid requirements, and fewer adverse effects compared to other opioids. Intraoperative methadone is not well studied in pediatric cardiac surgery. We hypothesized that intraoperative methadone-based analgesia would provide comparable effectiveness in pain management to non-methadone-based analgesia, including caudal morphine, following pediatric cardiac surgery. Methods: We conducted a retrospective cohort study of 287 children undergoing cardiac surgery using single institutional electronic health records with Society of Thoracic Surgeons database outcomes. Patients were administered intravenous opioids plus caudal morphine (≤6 years) or intravenous opioids in the non-methadone group versus intravenous methadone (two 0.1 mg/kg doses given intraoperatively) with or without additional intraoperative opioids. The primary outcome was postoperative opioid use in morphine milligram equivalents (MME)/kg. Results: This study included 287 pediatric cardiac surgical patients with a mean age of 3.8 years, 59% male, and 72% White. Among 287 patients, 67 (23%) received intraoperative methadone. Unadjusted analysis showed the methadone group had lower postoperative opioid use on the day of surgery (median = 0.3 vs. 0.5 MME/kg, p = 0.005). Adjusted analyses showed there were no significant differences in postoperative opioid use, average pain, maximum pain, antiemetic use, reintubation, and use of naloxone between methadone and non-methadone groups. Hospital length of stay was 2.62 times longer (95% CI: [1.55, 4.41] p < 0.001) in the methadone group vs non-methadone group, but this was only shown in the younger children (≤6 years), who also had higher max pain scores in the methadone group. All outcomes were similar between analgesia groups in older children (>6 years). Conclusions: Intraoperative methadone-based analgesia had comparable effectiveness in postoperative opioid use, pain, and antiemetic use compared to non-methadone-based intraoperative pain management for pediatric cardiac surgery. Large prospective studies of perioperative methadone are needed to examine methadone’s analgesic benefits in children undergoing cardiac surgery. Full article
(This article belongs to the Special Issue Future Directions in Pediatric Perioperative Care: Enhanced Recovery, Regional Analgesia and Personalized Medicine)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop