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Children
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State of the Art in Pediatric Anesthesia: Second Edition
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State of the Art in Pediatric Anesthesia: Second Edition

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Anesthesiology, Pain Medicine and Palliative Care".

Deadline for manuscript submissions: 25 October 2025 | Viewed by 971

Special Issue Editor

Prof. Dr. Senthilkumar Sadhasivam

E-Mail Website
Guest Editor
UPMC Children’s Hospital of Pittsburgh, Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, 4401 Penn Avenue, Pittsburgh, PA 15224, USA
Interests: pediatric and adult anesthesia; pain management; fetal anesthesia; regional anesthesia
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue will focus on current and evidence-based updates related to pediatric anesthesia and pain management in children. Specialists in the field are invited to submit original clinical research articles and high-quality evidence-based reviews. Preferred topics of interest include, but are not limited to, the following: anesthesia and perioperative pain relief for tonsillectomy in children; enhanced recovery after surgery in children; neonatal anesthesia; regional anesthesia and acute surgical pain management; opioid-free and opioid-sparing analgesia; perioperative methadone in children; anesthesia and staffing management in children's hospitals; pediatric airway management; common perioperative emergencies in children; management of children with complex medical history; pediatric cardiac anesthesia; pediatric transplant anesthesia; non-operating room anesthesia; and pediatric dental anesthesia.

We would additionally appreciate it if you could forward this to your team members and colleagues who may also be interested in the topic.

Thank you for your consideration. Please do not hesitate to contact us if you have any questions or suggestions.

Prof. Dr. Senthilkumar Sadhasivam
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anesthesia
  • children
  • surgical pain
  • opioids
  • regional anesthesia
  • pediatric anesthesia

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Related Special Issue

Published Papers (1 paper)

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Research

15 pages, 1154 KiB  
Article
Exploring the Interactions Between Epidural Analgesia, Extubation and Reintubation Outcomes in Infants in Neonatal Care Units: A Retrospective Cohort Study
by Mihaela Visoiu, Stephanie Parry, Tyler H. Augi, Danielle R. Lavage, Scott E. Licata, Holly A. Turula and Doreen E. Soliman
Children 2025, 12(3), 275; https://doi.org/10.3390/children12030275 - 24 Feb 2025
Viewed by 589
Abstract
Background/Objectives: Continuous epidural analgesia is desirable for improving infant outcomes after surgeries. However, its contribution to facilitating extubation is not well known. Methods: A retrospective chart review was conducted at the UPMC Children’s Hospital of Pittsburgh to identify all infants who received an [...] Read more.
Background/Objectives: Continuous epidural analgesia is desirable for improving infant outcomes after surgeries. However, its contribution to facilitating extubation is not well known. Methods: A retrospective chart review was conducted at the UPMC Children’s Hospital of Pittsburgh to identify all infants who received an epidural catheter between 2018 and 2024 and required postsurgical admission to the Neonatal Intensive Care Unit (NICU). The study examined the timing of extubation and reintubation, along with associated factors, in 100 infants who underwent major surgeries. Results: In total, 100 infants, 43 females and 57 males, 40 (38.39–42.07) weeks corrected gestational age, 3 (2.52–3.42) kg received epidural catheters. Sixty-two patients had a pulmonary condition. Of 45 infants extubated in the operating room, 32 received fentanyl intraoperatively, and 16 required a morphine infusion in the NICU. Among 55 infants that remained intubated, 24% underwent a thoracic procedure, 46 received intraoperatively fentanyl, and 21 needed an opioid infusion postoperatively. The extubation day was median (IQR) 2 (1–4), and 24% remained intubated beyond day 5. Twelve infants were intubated preoperatively, and six required prolonged ventilation beyond day 5. Of 15 infants that required reintubation, 8 received a morphine infusion. The medians (IQR) of the average of three pain and sedation scores before reintubation were 1.67 (1–3) and 0 (−1.67–0), respectively. Conclusions: Epidural analgesia may facilitate early extubation in some infants undergoing surgeries. Morphine infusion was administered at a similar rate between infants extubated and those who remained intubated, and its role in delaying extubation timing remains unclear. Full article
(This article belongs to the Special Issue State of the Art in Pediatric Anesthesia: Second Edition)
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