Non-IgE Pediatric Food Allergy: Clinical and Research Issues
A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Allergy and Immunology".
Deadline for manuscript submissions: 20 August 2025 | Viewed by 157
Special Issue Editors
2. Instituto de Investigación Sanitaria Gregorio Marañón (IISGM), Madrid, Spain
Interests: medicine; probiotics; microbiota; food-allergy; nutrition
Special Issue Information
Dear Colleagues,
The pathophysiology of non-IgE mediated food allergy is mostly unknown, and its incidence is increasing. This explains the lack of diagnostic and predictive markers for this entity, and its possible under-diagnosis. Unlike IgE-mediated allergy, the symptoms of non-IgE are typically delayed from hours to weeks after protein ingestion, and there is actually no confirmatory test available, so diagnosis can be a challenge. This problem impacts both allergy and gastrointestinal pediatricians but is usually handled differently because of its different manifestations. Some non-IgE diseases (eosinophilic esophagitis or enteropathy) are likely emerging due to immunotherapy or desensitization treatments.
The aim of this Special Issue is to encourage pediatric gastroenterologists and allergy specialists to share their experience in managing non-IgE disease. Cutting-edge studies could provide new biomarkers or new clinical scores for the diagnosis of non-IgE diseases, regarding any kind of food allergy. This research could provide new clinical tools for the monitoring of immune tolerance of food allergies.
We will consider original research articles, reviews, and case reports that explore novel diagnostic methods and biomarkers of non-IgE food allergy and early signs of oral immunotolerance failure.
Dr. Jimena Pérez-Moreno
Dr. María Elena Seoane-Reula
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- food allergy
- non-IgE-mediated allergy
- immunotherapy
- allergy management
- enteropathy
- eosinophilic esophagitis
- specific oral tolerance induction (SOTI)
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