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Clockwork Cells: Decoding the Language of Cell Cycle Regulators

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Proliferation and Division".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 4

Special Issue Editors


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Guest Editor
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA
Interests: cell cycle; cell-cell recognition; sexual reproduction; mating type; protists

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Guest Editor
National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Interests: cellular organization; higher-order assemblies; centrosomes; cell cycle; protein kinases

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Guest Editor
WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan
Interests: nuclear pore; intracellular transport; cell cycle; high-speed AFM; STED imaging; holotomography; machine learning; nano cell biology; nanomedicine
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, MA, USA
Interests: cell proliferation; differentiation; cell cycle control

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to this Special Issue on “Cell Cycle Regulators” in Cells. The cell cycle is fundamental to cellular proliferation, differentiation, and maintaining genomic stability. Cell cycle regulators emerged early in eukaryotic evolution and have since undergone remarkable diversification. Precise control of the cell cycle is essential for normal development and tissue homeostasis, while its dysregulation is a hallmark of numerous pathological conditions, including cancer, neurodegeneration, and aging.

This Special Issue aims to highlight recent advances in our understanding of the molecular mechanisms governing cell cycle progression, checkpoint control, and cell cycle arrest. We welcome studies exploring the functions of cyclins, cyclin-dependent kinases (CDKs), CDK inhibitors, tumor suppressors, and DNA damage response pathways. Additionally, we encourage submissions that investigate the diversity and evolution of cell cycle regulators across different species, which can offer novel insights into conserved and lineage-specific regulatory strategies.

By bringing together research from various biological systems and disciplines, this Special Issue seeks to provide a comprehensive and integrative view of cell cycle regulation, fostering cross-species comparisons and identifying emerging concepts that may inform future therapeutic or biotechnological applications.

Dr. Guanxiong Yan
Dr. Kyung-sang Lee
Prof. Dr. Richard W. Wong
Prof. Dr. Gary S. Stein
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cyclins
  • cyclin-dependent kinases (CDKs)
  • checkpoints
  • cell proliferation
  • mitosis
  • meiosis

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Published Papers

This special issue is now open for submission.
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