SARS-CoV-2—Cross-Talk on Cellular Pathways in Critically Ill Mechanically Ventilated Patients
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 499
Special Issue Editors
2. Clinic of Anaesthesia and Intensive Care, Emergency County Hospital “Pius Brinzeu”, Timisoara, Romania
3. Medical Education and Clinical Research Department, Romanian Society of Anesthesia and Intensive Care, Bucharest, Romania
Interests: anaesthesia; intensive care; antibiotics; biochemistry
Special Issues, Collections and Topics in MDPI journals
2. Clinic of Anaesthesia and Intensive Care, Emergency County Hospital "Pius Brinzeu", Timisoara, Romania
3. Medical Education and Clinical Research Department, Romanian Society of Anesthesia and Intensive Care, Bucharest, Romania
Interests: critical care; anaesthesia; biochemistry; molecular pathways
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The COVID-19 pandemic has challenged society worldwide. The large number of patients admitted to the hospital in a short time, the pathology and nonspecific symptoms of a new disease, and lack of protocols and treatments significantly hindered the activity of the medical system and its staff. Shortly after the identification of the new coronavirus, SARS-CoV-2, researchers around the world began attempting to identify and report the virus’ mechanisms of action, drug interactions, and molecular and epigenetic expressions. They also tried to identify therapeutic solutions to limit viral activity and its associated clinical effects.
The specific SARS-Cov-2 changes at the respiratory level, but also at the systemic inflammatory level, led to the rapid deterioration of patients’ clinical status, often rendering classical methods of mechanical ventilation ineffective.
An intensely studied field during this period was the expression of microRNA species, which contributed both to faster detection of the virus and to the development of new therapeutic technologies specific to these patients.
We invite you to submit this Special Issue, which aims to integrate new information on the topic, seeking fresh perspectives on the molecular and cellular changes induced by SARS-Cov-2, epigenetic expression of COVID-19 patients, expression of microRNAs in connection with SARS-Cov-2, virus detection methods, the clinically impact of SARS-Cov-2, new therapeutic methods, the impact of vaccination, etc.
Your research can include in vitro or in vivo studies or review articles on the following topics:
- MicroRNAs expression in COVID-19;
- New SARS-CoV-2 detection methods;
- New and specific therapeutic methods in COVID-19;
- Molecular and cellular changes induced by SARS-Cov-2;
- Expression of the inflammatory profile in COVID-19;
- Oxidative stress activity in patients infected with SARS-Cov-2;
- Mechanical ventilation models;
- Expression of mitochondrial activity in COVID-19;
- Changes in molecular and cellular pathways in the respiratory tract;
- Changes in molecular and cellular pathways in the nervous system;
- Sepsis and systemic inflammation syndrome;
- Histopathological analyses of COVID-19 patients.
We are looking forward to your contribution.
Prof. Dr. Dorel Sandesc
Dr. Alexandru Florin Rogobete
Guest Editors
Manuscript Submission Information
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Keywords
- COVID-19
- SARS-CoV-2
- microRNAs expression
- molecular pathways
- mechanical ventilation
- critically ill patients
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