Examining the Cellular Biology of Adenovirus
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 January 2026 | Viewed by 11
Special Issue Editors
Interests: adenovirus; viral vectors; adenovirus vaccine platform development; rapid manufacturing
Interests: viral vectors; adenovirus; adeno-associated virus; Epstein-Barr virus; gene regulation
Special Issue Information
Dear Colleagues,
Adenoviruses are non-enveloped, double-stranded DNA viruses typically 90–100 nm in size that cause a variety of respiratory, gastrointestinal and ocular infections in a range of host species. Since their discovery in 1953, they have provided crucial insights into cellular biological mechanisms such as eukaryotic transcription, RNA splicing and cell cycle control. The use of adenoviruses as a toolbox to study fundamental cellular biology has also expanded their use as therapeutic agents. In recent years, adenovirus vectors have been developed for use in oncolytic virotherapy, in gene therapy and as vaccines against diverse pathogens. For example, during the COVID-19 pandemic, 4 out of 12 emergency use licensed vaccines were derived from adenoviruses. In this Special Issue, we will compile both review and research articles focusing on adenovirus biology and cellular interactions. The scope of this issue will include, but will not be limited to, virus binding and entry, intracellular trafficking, replication and assembly. Understanding the fundamental mechanisms of adenovirus biology will help design and develop advanced therapeutics in the future.
Dr. Susan J. Morris
Dr. Adam C. T. Gillman
Dr. Erwan Sallard
Guest Editors
Manuscript Submission Information
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Keywords
- adenovirus
- replication
- maturation
- transduction
- tropism
- intracellular trafficking
- targeting
- virus–host interactions
- transcriptome
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