Role of Innate Immunity in Chronic Kidney Diseases—Series 2

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".

Deadline for manuscript submissions: closed (30 May 2024) | Viewed by 157

Special Issue Editor

E-Mail Website
Guest Editor
Katz Family Division of Nephrology and Hypertension, Miller School of Medicine, University of Miami, Miami, FL, USA
Interests: kidney; podocytes; lipids; lipid droplet; sphingolipids; innate immunity; diabetic kidney disease; focal segmental glomerulosclerosis
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Special Issue Information

Dear colleagues,

We are pleased to announce the second edition of our Special Issue. The first edition attracted the interest of researchers from around the world. The publications, which you are freely available to download, are listed at the link below:

Cells website:

Chronic kidney disease (CKD) is a worldwide health problem, with a global estimated prevalence of 16% and costs of USD 7.1 million for renal replacement therapy for patients with end-stage kidney disease. Among the multiple pathogenic mechanisms responsible for CKD, deregulated inflammation, oxidative stress, and immune system activation have deserved significant attention in recent years. More precisely, sterile inflammation triggered by the activation of the innate immune system has been shown to be an important driver of CKD. While our understanding of the innate immune system’s components and ligands, as well as its activation and regulation, has substantially improved in recent years, finding new drug targets and implementations of anti-inflammatory treatments for patients with CKD remains a challenge. This Special Issue will focus on different aspects of innate immunity involvement in CKD development and progression, including molecular, biochemical, and physiological mechanisms. We welcome original basic research and review articles related to the role of innate immunity in CKD.

Dr. Alla Mitrofanova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • CKD
  • glomeruli
  • tubules
  • sterile inflammation
  • innate immunity
  • pattern recognition receptors (PRRs)
  • damage-associated molecular patterns (DAMPs)
  • toll-like receptors
  • RIG-I
  • NLRP

Published Papers

There is no accepted submissions to this special issue at this moment.
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