Special Issue "New Insights Into Comprehensive Molecular Systems Regulating Cell Proliferation, Growth, and Cell Death"
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 June 2024 | Viewed by 137
Interests: regeneration; cell proliferation and cell growth; oxidative stress; cell death; optogenetics
Special Issues, Collections and Topics in MDPI journals
This Special Issue focuses on basic cellular events (“proliferation”, “growth”, and “death”) in the process of organ regeneration. If the organ is damaged and loses its function, it will immediately begin to regenerate and try to withhold its function. The regeneration process is complicated and unique depending on the organ, and therefore not yet fully elucidated.
In each organ, regeneration is achieved by smart and unique molecular machinery that coordinates cell proliferation, growth, and death. The proliferation of parenchymal/non-parenchymal cells is a central event of regeneration. Various kinds of pathological and mechanical stresses, such as ischemia–reperfusion or surgical resection, ignite the unique machinery by comprehensively regulating the initiation, continuation, and termination of regeneration. Similarly, cell growth plays a pivotal role in the achievement of quick and sure organ regeneration, especially in cases where cell proliferation is disturbed. The signals that regulate cell proliferation and growth interact each other to advance regeneration without delay. It is also important in all processes relating to regeneration to regulate cell death (programmed cell death or not). The signals of cell proliferation, growth, and survival are activated in the early regeneration phase, and often involved in the protection of cell death. Programmed cell death may play a key role to settle or terminate regeneration when sufficient function is recovered. At present, the precise mechanism of the cellular events mentioned above are not fully understood.
In this Special Issue, we expect papers on the molecular mechanisms that comprehensively regulate the interactions of cell proliferation, growth, survival, and death in organ regeneration in common or pathological situations. Studies on the molecular/cellular therapy of various diseases, surgical resection, and organ transplantation are also welcome.
Prof. Dr. Michitaka Ozaki
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- ischemia–reperfusion (hypoxia–reoxygenation) injury
- surgical resection
- cell proliferation
- cell growth
- programmed cell death
- oxidative stress
- signal transduction