Microscopy in Structural Biology Research

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Methods".

Deadline for manuscript submissions: 1 July 2025 | Viewed by 127

Special Issue Editor


E-Mail Website
Guest Editor
Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA
Interests: single-molecule biophysics; fluorescence; surface plasmons; molecular motors; viral DNA packaging

Special Issue Information

Dear Colleagues,

One of the most ubiquitous themes of biology is structure determining function. In this regard, microscopy techniques have produced a wealth of information about molecular, sub-cellular, and cellular architectures. This Special Issue focuses on current state-of-the-art microscopy used in structural biology research, including the following:

  1. Optical microscopy: This includes various modalities such as wide-field, confocal, Airyscan, STED (stimulated emission–depletion), super-resolution, CARS (coherent anti-Stokes Raman scattering), darkfield, near-field, fluorescence, and fluorescence resonance energy transfer (FRET) microscopy, to name a few.
  2. Electron microscopy: Both scanning and transmission instruments can determine the ultrastructure of biological samples by using single-particle reconstruction, 3D reconstruction using serial blockface imaging, and cryo-imaging.
  3. Atomic force microscopy: A non-radiative, scanning probe technique that is used to determine the topography of biological samples, including live cell samples, with nanoscale resolution. Additionally, the physical properties of biological samples can be determined, for example, the elastic modulus, adhesion, deformation, and energy dissipation.

Dr. Chandran R. Sabanayagam
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cryo-electron microscopy (Cryo-EM)
  • super-resolution microscopy
  • X-ray crystallography
  • structural biology
  • cellular architecture
  • biomolecular interactions
  • high-resolution structural analysis
  • integrative structural biology

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers

This special issue is now open for submission.
Back to TopTop