Epigenetic Regulatory Networks in Cancer: Understanding the Mechanisms of Disease Progression
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 606
Special Issue Editors
Interests: cancer; cell signaling; epigenetics; microRNA; targeted therapy; carcinogenesis; apoptosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer remains a significant clinical challenge due to its aggressive nature, treatment resistance, and the complexity of its underlying mechanisms. Despite advancements in understanding cancer pathogenesis, many forms of cancer continue to have poor prognoses and limited therapeutic options. Recent studies have highlighted the critical role of epigenetic regulatory mechanisms in the development and progression of various cancers. This Special Issue aims to explore the intricate epigenetic landscape that governs cancer pathogenesis, focusing on key components such as DNA methylation, histone modifications, non-coding RNAs—including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs)—and chromatin remodeling. These factors play a crucial role in regulating gene expression and cellular behavior, contributing to the initiation and advancement of cancer.
This Special Issue will highlight recent advancements in epigenetic research, focusing on novel biomarkers for early detection and potential therapeutic targets that could lead to more effective and personalized treatment strategies. By integrating these insights, the research presented here holds the potential to improve patient outcomes and offer new avenues in the fight against cancer. Additionally, it will enhance the understanding of how epigenetic alterations impact cancer biology, potentially informing strategies against a wide range of malignancies. We welcome submissions ranging from basic research to translational studies, aiming to provide a comprehensive overview of the epigenetic regulatory networks involved in cancer.
Dr. Anand Singh
Dr. Sudheer Kumar Gara
Guest Editors
Manuscript Submission Information
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Keywords
- cancer
- epigenetics
- miRNAs
- BAP1
- DNMTs
- tumor suppressor
- oncogenes
- histone modification
- chromatin remodeling
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