Novel Insights into the Biofilms
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (20 March 2025) | Viewed by 3208
Special Issue Editors
Interests: bacterial stress response; adaptation; biofilm and virulence; antimicrobial strategies
Special Issues, Collections and Topics in MDPI journals
Interests: bacterial biofilm; pathogenicity; antimicrobial strategies
Special Issue Information
Dear Colleagues,
It is well known that bacteria can switch from a planktonic unicelluar multiplication to a sessile non-motile assembly of cells encased in a extracellular matrix composed of polysaccharides, DNA, and proteins. Such multicellular structure forms what is called a biofilm. Biofilms are either attached to a surface such as epithelial cells or present as 3-dimensional aggregates as observed in the lungs of cystic fibrosis patients infected by Pseudomonas aeruginosa, a model microorganism for the study of biofilms. Bacterial biofilms are a dynamic structure evolving from attachment, microcolonies formation, maturation and decay allowing dispersion of newly formed planktonic cells. These different steps involve a cascade of several regulatory processes. Much attention focuses on ways to inhibit biofilm formation or to disperse already formed bofilms since planktonic cells are more sensitive to antibiotic treatments compared to the sessile cells protected by the extracellular matrix. This special issue on biofilms is open to all scientists involved in bacterial biofilm research including those interested in the regulation of biofilm development, biofilm dispersion, antibiotic and drug resistance, cells differentiation, matrix composition, mixed biofilms, and other aspects of biofilm research. Contributions focusing on the model microorganisms Pseudomonas aeruginosa and Staphylococcus aureus as well as studies on other bacterial species are welcome.
Prof. Dr. Sylvie Chevalier
Prof. Dr. Pierre Cornelis
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biofilms maturation
- biofilm matrix
- regulation
- dispersion
- eradication
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