Drosophila Models of Development and Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (20 December 2023) | Viewed by 7136
Special Issue Editor
Interests: intestine stem cells; tissue damage; homeostasis and regeneration; epithelial tumors and cell polarity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since Thomas Hunt Morgan and his students performed pioneering work using fruit flies to demonstrate that genes are located on chromosomes, as well as provided the first evidence for the concept of gene linkage, the fruit fly has been extensively used as a model organism for over a century to study a wide range of biological processes, including genetics, embryonic development, stem cells and organ regeneration, behavior, aging, among others. In addition, approximately 75% of all human disease-related genes have functional homologs in the fruit fly. Coupled with its low genetic redundancy, the fruit fly has been used to address specific questions about human diseases, such as neurological disorders, cancer, cardiovascular disease, metabolic and storage diseases, and more. By studying the molecular and cellular mechanisms of these diseases in the fruit fly, researchers can gain new insights into the underlying causes of disease and develop new strategies for treatment.
This Special Issue of the Journal of Cells will feature review-type articles and original research that highlight the power of Drosophila research in many aspects of development and human disease modeling.
Dr. Aiguo Tian
Guest Editor
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Keywords
- drosophila
- developmental biology
- diseases
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