Advances in the Gut–Liver–Brain Axis in Human Health and Disease
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 July 2026 | Viewed by 36
Special Issue Editor
Interests: gut–liver–brain axis; microbiota; metagenomics; stress; ionization radiation; fetal alcohol
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The gut–liver–brain axis is a dynamic communication system that links microbial, metabolic, immune, neural, and hormonal pathways to maintain human health. This axis plays a key role in maintaining both systemic and brain health through microbial metabolites, liver metabolism, immune signals, and neural pathways. Disruptions to this axis are linked to conditions such as metabolic syndrome, fatty liver disease, cirrhosis, neuroinflammation, neurodegeneration, and mood disorders.
This Special Issue will highlight new research to enhance our understanding of how this axis works, its role in disease, and its potential as a target for therapy. We invite original studies, reviews, and systematic analyses that bring together experimental, clinical, and translational insights. Submissions including multi‑omics, microbiome profiling, computational approaches, and precision medicine strategies are especially welcome.
This Special Issue will represent a platform to share new findings on how this axis influences disease and health. By connecting basic science and clinical research, it will encourage collaboration and guide the development of targeted treatments.
Dr. Pradeep K. Shukla
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut–liver–brain axis
- microbiota
- liver metabolism
- neuroinflammation
- metabolic disease
- neurodegeneration
- gut–brain communication
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