Molecular Mechanisms and Biomarker Development in Prostate Cancer
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 March 2026 | Viewed by 96
Special Issue Editors
Interests: genitourinary pathology; thoracic pathology
Special Issue Information
Dear Colleagues,
Different biological mechanisms have been associated with the development of prostate cancer, such as alterations in tumor suppressor genes, oncogenes (TP53, RB1, among others), and CDKIs; DNA methylation; chromosomal alterations and rearrangements; changes in PTEN and PI3K/mTOR; global defects in apoptosis; alterations in the androgen receptor (AR); and epigenetic mechanisms. The progress in the elucidation of the genomic, biochemical, and metabolic alterations of prostate cancer at various stages of disease development has promoted the identification of new potential therapeutic targets. This has led to the investigation of novel prostate cancer therapies: in these new therapeutic approaches the element of novelty is represented by the introduction of new drugs or of biomarkers to select patients to be treated. This Special Issue will examine various molecular alterations underlying the development of the prostate, with special emphasis on the development of biomarkers.
Dr. Vikas Mehta
Dr. Behtash Ghazi Nezami
Guest Editors
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Keywords
- androgen receptor
- prostate molecular alterations
- biomarkers
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