The Role of the Extracellular Vesicles in Kidney Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Microenvironment".
Deadline for manuscript submissions: 15 December 2025 | Viewed by 14
Special Issue Editors
Interests: precision medicine; extracellular vesicles (EVs); vasculogenesis; cell transplantation therapy; stem cell transplantation
Interests: extracellular vesicles; nano-extracellular vesicles; renal diseases; nephrology; regenerative medicine
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) have emerged as critical mediators of intercellular communication, playing pivotal roles in the pathogenesis, diagnosis, and treatment of kidney diseases. In chronic kidney disease (CKD) and acute kidney injury (AKI), EVs derived from various cell types carry molecular cargoes, including microRNAs (miRs), that can modulate inflammatory responses, fibrosis, and tissue repair. Recent advances position EVs and miRs as promising regenerative products, offering novel therapeutic strategies to restore renal function and mitigate disease progression. Furthermore, the diagnostic potential of EVs enriched with disease-specific miRs is increasingly recognized, opening new avenues for non-invasive biomarkers in nephrology and urology. As the complexity of EV and miR interactions continues to unfold, artificial intelligence (AI) integration is becoming essential for the analysis and interpretation of large-scale EV datasets. AI-driven approaches can enhance the identification of predictive biomarkers, personalize treatment strategies, and accelerate the development of EV-based therapeutics. This Special Issue invites original research and reviews focused on the innovative applications of EVs and miRs in kidney diseases, regenerative medicine, biomarker discovery, and AI-driven diagnostics and therapeutics in nephrology and urology.
Dr. Amankeldi Salybekov
Dr. Ciro Tetta
Guest Editors
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Keywords
- extracellular vesicles (EVs)
- microRNAs (miRs)
- chronic kidney disease (CKD)
- acute kidney injury (AKI)
- regenerative medicine
- biomarkers
- artificial intelligence (AI)
- nephrology
- urology
- precision medicine
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