Molecular Mechanisms and Pathophysiology of Diabetic Retinopathy
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 15 April 2026 | Viewed by 1463
Special Issue Editors
Interests: diabetic retinopathy; pathophysiology of diabetic complications; diabetic nephropathy; chronic kidney disease; inflammation; oxidative stress
Interests: retinopathy; glaucoma; retinal ganglion cell physiology; retinal pigment cell biology and pathophysiology
Interests: age-related macular degeneration; epithelial-to-mesenchymal transition; retinal pigment epithelial cell in disease pathophysiology; oxidative stress; inflammation
Special Issue Information
Dear Colleagues,
Diabetic retinopathy (DR) remains the leading cause of blindness, yet little is known about the molecular processes that lead to retinal abnormalities and vision impairments brought on by diabetes. Elucidating the mechanisms underlying the pathophysiology and treatments of DR remains a major focus of research, with the ultimate goal of developing intervention strategies that attenuate microvascular complications and structural and functional degeneration of the retina. As effective therapies for DR are currently lacking, input from a wide array of fields, including physiology, ophthalmology, and endocrinology, appears to be the need of the hour.
Studies aimed at treating or curing DR are notable for the ways in which basic and translational research, as well as clinical practice, inform one another and produce novel therapeutic modalities. Recent methodological innovations in single-cell transcriptomics, proteomics, and drug target discovery have generated significant advancements. This Special Issue invites manuscript submissions, namely original research articles and review papers, to provide a collection of the current knowledge and advances in understanding the cellular and molecular pathophysiology of DR. Of specific interest are papers focused on the discovery and characterization of novel drug targets, cell signaling pathways, and molecular mechanisms regulating structural and functional degeneration of the retina and vascular complications in DR.
Dr. Siddharth Sunilkumar
Dr. Stephanie L. Grillo
Dr. Sandeep M. Subrahmanian
Guest Editors
Manuscript Submission Information
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Keywords
- diabetic retinopathy
- retina
- retinal neurodegeneration
- diabetic macular edema
- pathophysiology of diabetic retinopathy
- proliferative and non-proliferative diabetic retinopathy
- molecular mediators of diabetic retinopathy
- cell-based therapies for diabetic retinopathy
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