GABAA Receptor Dynamics: From Cellular Quality Control to Disease Mechanisms
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 March 2026 | Viewed by 13
Special Issue Editors
Interests: GABAA receptors; proteostasis; trafficking; disease mechanisms
Special Issue Information
Dear Colleagues,
GABAA receptors are principal mediators of fast inhibitory neurotransmission in the mammalian brain and are essential for maintaining the balance between neuronal excitation and inhibition. Their proper function is intrinsically linked to dynamic cellular processes, including biogenesis, protein quality control (proteostasis), and trafficking mechanisms that dictate their localization and composition on the neuronal surface. Disruption in these dynamic cellular processes, often resulting from genetic variants or impaired proteostasis, is increasingly recognized as a key driver of neurological and psychiatric disorders, such as epilepsy, anxiety, autism spectrum disorders, and schizophrenia.
This Special Issue of Cells, GABAA Receptor Dynamics: From Cellular Quality Control to Disease Mechanisms, invites original research articles and reviews focused on the molecular and cellular regulation of GABAA receptors. Topics of interest include, but are not limited to, receptor folding, receptor assembly, protein quality control, degradation pathways, membrane trafficking, receptor structure and function, and the impact of genetic and disease-associated perturbations. By bringing together new insights across disciplines, this issue aims to deepen our understanding of GABAA receptor biology and its relevance to brain health and disease.
Dr. Tingwei Mu
Dr. Yajuan Wang
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- GABAA receptors
- trafficking
- biogenesis
- proteostasis
- structure and function
- gating
- neurotransmission
- neurological diseases
- disease mechanisms
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
