New Insights into Channelopathies
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (28 February 2025) | Viewed by 247
Special Issue Editors
Interests: bone; cell cycle; akt; Ca2+-activated K+(BK) channel; calcium ions; cell volume; trp channels; KATP and Kir channels
Special Issues, Collections and Topics in MDPI journals
Interests: channelopathies of gastrointestinal apparatus; pathophysiology of the gastrointestinal apparatus
Special Issue Information
Dear Colleagues,
Channelopathies, disorders characterized by the dysfunction of ion channels, offer a rich tapestry of cellular and molecular complexity. This Special Issue is dedicated to exploring the intricate mechanisms at the cellular and molecular levels that underlie these conditions. We aim to provide a comprehensive view of the current understanding of channelopathies, focusing on the fundamental aspects that are central to their pathogenesis.
Ion channels are critical for maintaining the delicate balance of ion concentrations across cellular membranes, which is essential for processes such as signal transmission in the nervous system and muscle contraction. The articles in this issue delve into the structural biology of these channels, examining how mutations can alter their function and induce disease. We explore the genetic landscape, highlighting how specific mutations can affect channel properties and contribute to the development of channelopathies.
This issue also features insights into the cellular consequences of ion channel dysfunction, discussing how these disruptions can impact cellular signaling pathways and homeostasis. The innovative diagnostic approaches highlighted here are designed to detect these molecular aberrations, offering the potential for an earlier and more precise identification of channelopathies.
By concentrating on the cellular and molecular aspects, this Special Issue aims to advance our knowledge of channelopathies, inspire new research directions, and contribute to the development of targeted therapeutic strategies. We hope that the insights presented will serve as a foundation for future discoveries and a catalyst for progress in this fascinating field.
Prof. Dr. Domenico Tricarico
Dr. Fatima Maqoud
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- channelopathies
- ion channels
- cellular and molecular mechanisms
- pathogenesis
- signaling
- potassium channel
- sodium channel
- calcium channel
- voltage-gated ion channel
- TRP channel
- therapeutic strategies
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