Mesenchymal Stem/Stromal Cell Therapies: Innovations in Regenerative Medicine and Translational Applications

Dear Colleagues,

Human mesenchymal stem/stromal cells (hMSCs), as has been known for years, have extraordinary differentiation potential toward various lineages, namely adipogenic, chondrogenic, and osteogenic, as well as hepatic and pancreatic. Furthermore, their immunomodulatory properties make them a promising tool for application in the field of regenerative medicine. Based on extensive in vitro evidence, the immunological effects of MSCs on immune cells may depend on various mechanisms, such as cell-to-cell contact and paracrine signaling. MSCs also release exosomes capable of exerting various effects in a paracrine manner, influencing inflammatory processes.

This Special Issue of Cells will highlight the cell biology and immunology of MSCS through original research articles, reviews, and communications.

Dr. Giandomenico Amico
Dr. Paolo Elia Cappella
Guest Editors

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