Special Issue "Multi-Step Syntheses in Biology & Chemistry"

A special issue of Catalysts (ISSN 2073-4344).

Deadline for manuscript submissions: 30 April 2020.

Special Issue Editor

Guest Editor
Prof. Dr. Harald Gröger Website E-Mail
Chair of Industrial Organic Chemistry and Biotechnology, Faculty of Chemistry, Bielefeld University, Universitätsstrasse 25, 33615 Bielefeld, Germany
Interests: enzymatic processes; biocatalytic syntheses with whole cell-catalysts; chemoenzymatic one-pot processes; biocatalytic synthesis of industrial products; technical bio- and chemocatalytic processes

Special Issue Information

Dear Colleagues,

Bio- and chemocatalysis are among today’s key technologies that will shape not only the industrial landscape but also our daily lives in the future. This interdisciplinary field of research, which combines biology and chemistry, opens great perspectives for basic research as well as for industrial applications. A particular opportunity and, at the same time, a challenge is to combine various synthetic steps catalyzed by enzymes and/or man-made catalysts towards multi-step syntheses. Such synthetic cascades can enable novel pathways to obtain the molecules required by various components of the industrial product tree, e.g., pharmaceuticals. The combination of individual steps for a compound synthesis can proceed in a sequential fashion with intermediate isolation of the product of interest or by merging these reactions within a one-pot cascade. Such processes consisting of multiple steps might be based only on the use of enzymes or chemocatalysts or can be realized by integrating both “worlds of catalysts” within a synthetic pathway. Addressing these fascinating research areas, this Special Issue will focus on the fields of tailor-made bio-catalyst design and applications thereof, combination of biocatalysis and chemocatalysis, and synthetic biology towards multi-step syntheses from both an academic and an industrial perspective. In addition, recent trends, so far mostly emerging from the area of chemocatalysis but expected to have a strong impact on biocatalysis in the future, will be addressed such as, for example, flow chemistry and machine learning self-automatization. Although this Special Issue is being organized on the occasion of the 13th International CeBiTec Symposium “Multi-Step Syntheses in Biology & Chemistry—An International Young Investigator Conference” that will be held at Bielefeld University on December 2–4, 2019, the invitation to submit manuscripts is open to all colleagues active in this research field. Thus, submission of manuscripts from researchers reporting their latest results on these above-mentioned topics are very much welcome.

Prof. Dr. Harald Gröger
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Biocatalysis
  • cascades
  • chemocatalysis
  • enzyme catalysis
  • fine chemicals
  • flow chemistry
  • industrial synthesis
  • multi-step synthesis
  • natural products
  • one-pot processes
  • pharmaceutical intermediates
  • pharmaceuticals
  • self-automatization

Published Papers

This special issue is now open for submission.
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