State-of-the-Art Enzyme Engineering and Biocatalysis in Europe

A special issue of Catalysts (ISSN 2073-4344). This special issue belongs to the section "Biocatalysis".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 24

Special Issue Editors


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Guest Editor
Department of Drug Sciences, University of Pavia, Viale Taramelli 12, I-27100 Pavia, Italy
Interests: chemoenzymatic synthesis; medicinal chemistry; biocatalysis; protein engineering
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Drug Sciences, University of Pavia, Viale Taramelli 12, I-27100 Pavia, Italy
Interests: biocatalysis; chemoenzymatic synthesis; enzyme production and purification in recombinant form; crystallography

Special Issue Information

Dear Colleagues,

Enzyme engineering and biocatalysis represent key technologies at the interface of molecular biology, chemistry, and process engineering, offering sustainable and efficient solutions for the production of pharmaceuticals, fine chemicals, agrochemicals, bio-based materials, and more. Europe has a distinguished tradition of excellence in this field, actively driving innovation through interdisciplinary collaborations and robust industrial partnerships.

In alignment with the priorities of the European Green Deal and the objectives of Horizon Europe, this Special Issue aims to highlight the role of enzyme engineering and biocatalysis in advancing green and circular economy goals, reducing environmental impact, fostering an efficient use of resources, and enabling the sustainable production of pharmaceuticals, fine chemicals, and bio-based products.

To this end, we welcome submissions of original research articles and review papers. Topics of interest include, but are not limited to, the following:

  • Rational design and directed evolution of enzymes for improved performance and selectivity.
  • Biocatalytic approaches for the sustainable synthesis of pharmaceuticals, fine chemicals, and value-added products.
  • Insights into enzyme structure–function relationships and catalytic mechanisms.
  • Innovative strategies for enzyme immobilization and process intensification.
  • Development of multi-enzyme cascade reactions and integration with chemical catalysis.
  • Application of computational methods and artificial intelligence in enzyme design and pathway optimization.
  • Advances in bioprocess engineering for scalable and efficient biocatalytic production.

We are confident that this Special Issue will provide an inspiring overview of the state of enzyme engineering and biocatalysis in Europe, fostering collaboration and innovation across the scientific community, while contributing to the overarching goals of European research and sustainable development.

Dr. Teodora Bavaro
Dr. Marina S. Robescu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • enzyme engineering
  • biocatalysis
  • directed evolution
  • enzyme immobilization
  • multi-enzyme cascade reactions
  • bioprocess engineering
  • chemoenzymatic synthesis

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Published Papers

This special issue is now open for submission.
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