The Unseen Burden: Incidence and Outcomes of Infections in Leukemia

Dear Colleagues,

Infections remain a leading cause of morbidity and mortality in patients with acute leukemia, profoundly impacting treatment outcomes and quality of life. Clinicians face a formidable challenge as they navigate the evolving landscape of new target therapeutic strategies, which is complicated by the rise of multidrug-resistant pathogens.

This Special Issue aims to provide a comprehensive and timely overview of the complex landscape of infectious complications in patients with acute leukemia. We aim to explore key areas, from a deeper understanding of the host–microbe interactions that shape infection risk to the impact of new therapeutic regimens on immune homeostasis and infection risk. We also hope to expand scientific knowledge about advances in diagnostic and therapeutic strategies, offering critical insights to optimize patient management and improve survival. This collection serves as a vital resource for hematologists and infectious disease specialists, highlighting the persistent threat of infections and guiding the way toward a safer, more effective approach to leukemia care.

Dr. Elisa Buzzatti
Dr. Maria Ilaria Del Principe
Guest Editors

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