Utilizing Nanoparticles in Cancer Immunotherapy: Innovations and Challenges
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (29 March 2024) | Viewed by 1327
Special Issue Editors
Interests: drug resistance; immunotherapy; 3D tissue cultures; nanoparticles; cancer biology
Special Issues, Collections and Topics in MDPI journals
Interests: immune cell signaling; T cell biology; tumor immunology; immune regulation; autoimmune diseases
Special Issue Information
Dear Colleagues,
This Special Issue, entitled “Utilizing Nanoparticles in Cancer Immunotherapy: Innovations and Challenges”, aims to act as a comprehensive guide that provides insight into the innovative incorporation of nanotechnology into cancer immunotherapy. This resource elucidates how nanoparticles enhance the delivery and efficacy of immunotherapeutic agents, including peptides, antibodies, small molecules, and nucleic acids. It showcases the potential of nanoparticles in modulating the tumor microenvironment, improving antigen transport to immune cells, and inducing immunogenic cell death. Additionally, this Special Issue discusses novel nanotechnological strategies for overcoming the limitations of traditional immunotherapies, such as low response rates and side effects. Cutting-edge developments like stimulus-responsive nanocarriers and combinatorial therapies are examined for their potential in combating cancer resistance. Lastly, this Special Issue outlines the current clinical applications and the future trajectory of nanoparticles in cancer immunotherapy by covering the following topics:
- Introduction to nanoparticles and their role in immunotherapy;
- Types of nanoparticles and their biomedical applications;
- Enhancing the delivery of immunotherapeutic agents through nanoparticles;
- Modulating the tumor microenvironment (TME) with nanoparticles;
- Improving antigen transport and presentation via nanoparticles;
- Inducing immunogenic cell death using nanoparticle-based strategies;
- Overcoming limitations of traditional immunotherapies through nanotechnology;
- Stimulus-responsive nanocarriers and their role in targeted therapy;
- Combinatorial therapies: integrating nanoparticles with other treatment modalities;
- Current clinical applications and future prospects of nanoparticles in cancer immunotherapy.
Dr. Abdel Kareem Azab
Prof. Dr. Linrong Lu
Guest Editors
Manuscript Submission Information
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Keywords
- nanoparticles
- cancer immunotherapy
- tumor microenvironment
- targeted drug delivery
- combinatorial therapies
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