Diagnosis and Treatment of Post-Stroke and Progressive Aphasias
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurolinguistics".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 546
Special Issue Editors
Interests: aphasia; aphasia treatment; neuroimaging; cognitive science
Special Issue Information
Dear Colleagues,
Aphasia is a common language disorder caused by neurological diseases. The scientific history of aphasia began over 100 years ago, during the “golden age” of neurology, with Broca’s discoveries, raising interest in the more precise localization of brain disorders. Significant clinical contributions and notable advances in theoretical formulation were made during the first few decades of the 19th century, followed by the 20th century advances in neuroimaging and the most recent data-driven approaches to deliver better classification and lesion-based predictions in post-stroke patients. Lately, the study of aphasia has expanded to include a newly discovered clinical entity, primary progressive aphasia (PPA), which, although broadening our knowledge about aphasia phenotypes, extended the discrepancy between clinical impressions and classification systems among language disorders. Although a huge number of individuals with post-stroke aphasia can have improved outcomes with behavioral therapy, there is a need to develop new and emerging technologies to improve the quality of life for patients who suffer from both stroke-induced and primary progressive aphasia, and to facilitate early diagnoses and focusing on slowing down the progression in PPA.
This Special Issue will primarily address (i) the clinical categorization of patients with aphasia, (ii) highlight advances in the diagnosis and treatment of aphasia, and finally (iii) define the best modalities to include imaging techniques and machine-learning approaches to facilitate and predict outcomes. The aims of this Special Issue are to offer more personalized and granular predictive modeling of rehabilitation, understand the hidden neural markers of vulnerability and disease, and characterize the anatomical substrate of aphasia.
Dr. Sigfus Kristinsson
Dr. Sladjana Lukic
Guest Editors
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Keywords
- post-stroke aphasia
- primary progressive aphasia
- lesion–symptom mapping
- neuroimaging
- speech and language treatment
- neural markers
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