Recent Advances in Stem Cell Therapy for Brain Disease
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Molecular and Cellular Neuroscience".
Deadline for manuscript submissions: closed (25 May 2024) | Viewed by 214
Special Issue Editors
Interests: neural repair; stem cells therapy; biomaterials; experimental models; central nervous system
Special Issues, Collections and Topics in MDPI journals
Interests: ALS; MS; cerebrovascular pathologies; stroke
Special Issues, Collections and Topics in MDPI journals
Interests: multiple sclerosis; neurodegenerative diseases; neural repair; neuromolecular mechanisms; long COVID
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, stem cell therapy has emerged as a promising and advanced scientific research topic. Stem cells possess the unique ability to continuously replenish themselves, called “self-renewal”, and develop into many different types of cells comprising the human body (via a process of “differentiation”), such as muscle cells, blood cells, or brain cells. Stem cell therapy is a branch of regenerative medicine that aims to enhance the body's repair machinery via stimulation, modulation, and regulation of the endogenous stem cell population, and/or by replenishing the cell pool, contributing toward tissue homeostasis and regeneration. Medical treatments are already having an impact on patients in a clinical setting. The flexibility and adaptability of these cells make them especially exciting new therapeutic options, both for rebuilding damaged brain tissues and for combatting neurodegenerative diseases. In recent decades, researchers found significantly improved outcomes for mesenchymal stem cell-treated patients compared with those receiving sham treatment. MSCs are well known for their homing capacity, immunomodulatory effects, and secretion of paracrine factors to repair tissues and induce functional recovery. In fact, the effect of paracrine modulation through the secretion of bioactive molecules, including lipids, proteins, free nucleic acids and different types of extracellular vesicles (EV), is well documented.
This Special Issue invites authors and researchers to participate in the discussion and exploration with contributions of both articles and reviews, expanding our understanding of the use of stem cells in neuroscience.
Dr. Alejandro Arturo Canales-Aguirre
Dr. Ulises Gomez-Pinedo
Dr. Jorge Matias-Guiu
Guest Editors
Manuscript Submission Information
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Keywords
- stem cells
- cell therapy
- neurodegenerative diseases
- cell differentiation
- neuroregeneration
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