Biosensors for Physiological Signal Monitoring

Dear Colleagues,

The convergence of flexible electronics and biomarker sensing has revolutionized continuous health monitoring. Wearable biosensors now enable multimodal tracking of electrophysiological signals (i.e., EEG, ECG, EMG, EOG, and EDA), biomechanical parameters (i.e., strain and pressure), and biochemical analytes (i.e., glucose, lactate, cortisol, and pH). These platforms provide unprecedented insights into physiological states, from cardiovascular health to emotional stress and cognitive fatigue.

This Special Issue highlights innovations in materials, device architectures, and signal processing that advance epidermal sensing systems. We prioritize solutions addressing critical wearable challenges: motion artifact suppression, skin-interfacing reliability, and long-term biosignal fidelity. Emerging technologies integrating machine learning for real-time health diagnostics are of particular interest.

We invite contributions on the following:

• Novel flexible substrates and electrodes for robust biosignal acquisition;
• Multiplexed sensor arrays for concurrent physical or biochemical monitoring;
• Energy-efficient wireless interfaces and edge-computing architectures;
• Anti-fouling coatings and biocompatible adhesion strategies;
• Fusion algorithms and AI models for cross-modal physiological data interpretation;
• Clinical validation studies of wearable health prediction models;
• Biosensors for brain–computer interfaces, human–machine interactions and health monitoring.

Both fundamental research and translational applications are welcome, with an emphasis on scalable manufacturing and user-centric design.

Dr. Guangli Li
Prof. Dr. Xueye Chen
Dr. Bowen Ji
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

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