Current Perspectives in Biocatalytic Biosensors

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1947

Special Issue Editors


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Guest Editor
1. Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona, 4-70125 Bari, Italy
2. CSGI (Centre for Colloid and Surface Science), Via E. Orabona, 4-70125 Bari, Italy
Interests: wearable biosensors; biofuel cells; redox polymers; printing enzymes; redox proteins
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona, 4 -70125 Bari, Italy
2. CSGI - Center for Colloid and Surface Science, CSGI@UniBa, Via E. Orabona, 4 -70125 Bari, Italy
Interests: biosensors; EGOFET; self-assembled monolayers; stencil printing; wearable biosensors

Special Issue Information

Dear Colleagues,

In recent years, we have witnessed the development of a number of biocatalytic biosensors as end-user and time-saving analytical devices for analyte detection in the fields of food, clinical and environmental sensing. Among all the transduction techniques under consideration, research into biocatalytic biosensors has mostly focused on amperometric devices.

Enzymes were historically the first molecular recognition elements included in biocatalytic biosensors, but it is now possible to rely on several biocatalysts (e.g., catalytic DNA strands, nanozymes, smart hydrogels etc.). Nowadays, billions of people are surrounded by biocatlaytic biosensors despite their relatively young age of only 60 years! In this period, many researchers, dealing mostly with the same target molecules as in early times, have developed novel strategies to tackle electron transfer issues and to realize stable, sensitive, and selective biosensors.

This Special Issue devoted to biocatalytic biosensors (e.g., amperometric, potentiometric etc.) aims to focus on the most recent advances in the development of highly sensitive, selective and stable biosensors for food-related, biomedical and environmental applications.

Prof. Dr. Paolo Bollella
Dr. Angelo Tricase
Guest Editors

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Keywords

  • enzyme biosensors
  • smart hydrogels
  • printed enzymes
  • catalytic DNA
  • nanozymes
  • nanomaterials

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Published Papers (1 paper)

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Research

14 pages, 7985 KiB  
Article
Flexible Graphene Paper Modified Using Pt&Pd Alloy Nanoparticles Decorated Nanoporous Gold Support for the Electrochemical Sensing of Small Molecular Biomarkers
by Encheng Sun, Zhenqi Gu, Haoran Li, Xiao Liu, Yuan Li and Fei Xiao
Biosensors 2024, 14(4), 172; https://doi.org/10.3390/bios14040172 - 3 Apr 2024
Cited by 1 | Viewed by 1445
Abstract
The exploration into nanomaterial-based nonenzymatic biosensors with superb performance in terms of good sensitivity and anti-interference ability in disease marker monitoring has always attained undoubted priority in sensing systems. In this work, we report the design and synthesis of a highly active nanocatalyst, [...] Read more.
The exploration into nanomaterial-based nonenzymatic biosensors with superb performance in terms of good sensitivity and anti-interference ability in disease marker monitoring has always attained undoubted priority in sensing systems. In this work, we report the design and synthesis of a highly active nanocatalyst, i.e., palladium and platinum nanoparticles (Pt&Pd-NPs) decorated ultrathin nanoporous gold (NPG) film, which is modified on a homemade graphene paper (GP) to develop a high-performance freestanding and flexible nanohybrid electrode. Owing to the structural characteristics the robust GP electrode substrate, and high electrochemically catalytic activities and durability of the permeable NPG support and ultrafine and high-density Pt&Pd-NPs on it, the resultant Pt&Pd-NPs–NPG/GP electrode exhibits excellent sensing performance of low detection limitation, high sensitivity and anti-interference capability, good reproducibility and long-term stability for the detection of small molecular biomarkers hydrogen peroxide (H2O2) and glucose (Glu), and has been applied to the monitoring of H2O2 in different types of live cells and Glu in body fluids such as urine and fingertip blood, which is of great significance for the clinical diagnosis and prognosis in point-of-care testing. Full article
(This article belongs to the Special Issue Current Perspectives in Biocatalytic Biosensors)
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