Special Issue "NanoBioSensors for Biomedical, Environmental and Food Monitoring Applications"

A special issue of Biosensors (ISSN 2079-6374).

Deadline for manuscript submissions: closed (31 January 2019)

Special Issue Editor

Guest Editor
Prof. Dr. Monica Florescu

Transilvania University of Brasov, Faculty of Medicine, Brasov, Romania
Website | E-Mail
Interests: biophysics; electrochemical and optical nanosensors/nanobiosensors for medical applications; biomolecular interactions

Special Issue Information

Dear Colleagues,

Biosensors have earned considerable interest in recent years, and they show great promise for a wide range of applications in biological research, medical diagnostics, environmental or food industry monitoring. Making use of the synergetic effect between nanotechnology, biomolecules and different detection methods has enabled nanobiosensors development for faster detection and its reproducibility in a much better way.

We invite, for this “NanoBioSensors for Biomedical, Environmental and Food Monitoring Applications” Special Issue, manuscripts dealing with different detection methods-based nanobiosensors for application fields mentioned above, while not being limited to those, which will be or not presented in the frame of the International Conference, IC-ANMBES 2018, held in Brasov, Romania (https://sciforum.net/conference/icanmbes2018). Both original research and review articles are welcome.

Original research papers that describe the development, characterization/evaluation, simulations and utilization of different architectures (sensor, fixed, mobile) platforms for detection of biological active or toxic compounds in complex samples with potential applications in medical analysis and diagnosis, environmental or food industry monitoring are of interest. The manuscripts can deal with next topics (but are not limited to) with potential relevance to nanobiosensing:

- microfluidics and point-of-care microdevices,
- optical fibers,
- mass-sensitive chips,
- novel materials electrodes and surface functionalization strategies applications or
- new concepts and fundamental studies.

Reviews should provide an up-to-date and critical overview of state-of-the-art of platforms and detection mechanisms, especially those used for nanobiosensing.

Please feel free to contact us and send us your suggestions that you would like to discuss beforehand. We look forward to and welcome your participation in this Special Issue.

Prof. Dr. Monica Florescu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 650 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Nanotechnology
  • Nanobiosensors
  • Microfluidics
  • Point-of-care microdevices
  • Novel materials
  • Surface functionalization

Published Papers (1 paper)

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Open AccessArticle
Electrochemical Sensor Based on Molecularly Imprinted Polymer for the Detection of Cefalexin
Biosensors 2019, 9(1), 31; https://doi.org/10.3390/bios9010031
Received: 18 December 2018 / Revised: 5 February 2019 / Accepted: 22 February 2019 / Published: 27 February 2019
PDF Full-text (2149 KB) | HTML Full-text | XML Full-text | Supplementary Files
In this study, a new electrochemical sensor was developed for the detection of cefalexin (CFX), based on the use of a molecularly imprinted polymer (MIP) obtained by electro‒polymerization in an aqueous medium of indole-3-acetic acid (I3AA) on a glassy carbon electrode (GCE) and [...] Read more.
In this study, a new electrochemical sensor was developed for the detection of cefalexin (CFX), based on the use of a molecularly imprinted polymer (MIP) obtained by electro‒polymerization in an aqueous medium of indole-3-acetic acid (I3AA) on a glassy carbon electrode (GCE) and on boron-doped diamond electrode (BDDE). The two different electrodes were used in order to assess how their structural differences and the difference in the potential applied during electrogeneration of the MIP translate to the performances of the MIP sensor. The quantification of CFX was performed by using the electrochemical signal of a redox probe before and after the rebinding of the template. The modified electrode was characterized using atomic force microscopy (AFM), scanning electron microscopy (SEM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The influence of different parameters on the fabrication of the sensor was tested, and the optimized method presented high selectivity and sensitivity. The MIP-based electrode presented a linear response for CFX concentration range of 10 to 1000 nM, and a limit of detection of 3.2 nM and 4.9 nM was obtained for the BDDE and the GCE, respectively. The activity of the sensor was successfully tested in the presence of some other cephalosporins and of other pharmaceutical compounds. The developed method was successfully applied to the detection of cefalexin from real environmental and pharmaceutical samples. Full article

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