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Biosensors
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Biosensing Based on Nanohybrid Materials
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Biosensing Based on Nanohybrid Materials

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: closed (19 October 2024) | Viewed by 3404

Special Issue Editor

Dr. Nancy Fabiana Ferreyra

E-Mail Website
Guest Editor
Instituto de Investigaciones en Fisicoquímica de Córdoba (INFIQC-CONICET-UNC), Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba X5000HUA, Argentina
Interests: enzymatic biosensors; glycobiosensors; bioelectrochemistry; magnetic nanoparticles; carbon nanotubes; biopolymers; nanobiotechnology

Special Issue Information

Dear Colleagues,

In recent years, various polymers have been extensively used to develop biosensors. The applicability of these materials increased with the combination of two or three other materials. In this context, the development of hybrid material-based biosensors to be used as medical diagnostic tools, as well as in food analysis or environmental monitoring has garnered traction.

Given this context, we are pleased to announce the launch of this Special Issue, entitled ‘Biosensing Based on Nanohybrid Materials’, which aims to collate research concerning the design, characterization, and fabrication of biosensors based on nanohybrid materials, with potential applications in the detection of metabolites of clinical interest, pharmaceuticals, food analysis, and environmental monitoring. We welcome submissions of original research articles, communications, and reviews.

Dr. Nancy Fabiana Ferreyra
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanohybrids composites
  • biosensors
  • electrochemical sensors
  • optical biosensors
  • food analysis
  • environmental monitoring

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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17 pages, 2890 KiB  
Article
Immobilization of Horseradish Peroxidase onto Montmorillonite/Glucosamine–Chitosan Composite for Electrochemical Biosensing of Polyphenols
by María Belén Piccoli, Florencia Alejandra Gulotta, Mariana Angélica Montenegro, Noelia Luciana Vanden Braber, Verónica Irene Paz Zanini and Nancy Fabiana Ferreyra
Biosensors 2024, 14(6), 278; https://doi.org/10.3390/bios14060278 - 29 May 2024
Cited by 1 | Viewed by 1376
Abstract
Glucosamine–chitosan synthesized by the Maillard reaction was combined with montmorillonite to obtain a nanohybrid composite to immobilize horseradish peroxidase. The material combines the advantageous properties of clay with those of the chitosan derivative; has improved water solubility and reduced molecular weight and viscosity; [...] Read more.
Glucosamine–chitosan synthesized by the Maillard reaction was combined with montmorillonite to obtain a nanohybrid composite to immobilize horseradish peroxidase. The material combines the advantageous properties of clay with those of the chitosan derivative; has improved water solubility and reduced molecular weight and viscosity; involves an eco-friendly synthesis; and exhibits ion exchange capacity, good adhesiveness, and a large specific surface area for enzyme adsorption. The physicochemical characteristics of the composite were analyzed by infrared spectroscopy and X-ray diffraction to determine clay–polycation interactions. The electrochemical response of the different polyphenols to glassy carbon electrodes modified with the composite was evaluated by cyclic voltammetry. The sensitivity and detection limit values obtained with the biosensor toward hydroquinone, chlorogenic acid, catechol, and resorcinol are (1.6 ± 0.2) × 102 µA mM−1 and (74 ± 8) nM; (1.2 ± 0.1) × 102 µA mM−1 and (26 ± 3) nM; (16 ± 2) µA mM−1 and (0.74 ± 0.09) μM; and (3.7± 0.3) µA mM−1 and (3.3 ± 0.2) μM, respectively. The biosensor was applied to quantify polyphenols in pennyroyal and lemon verbena extracts. Full article
(This article belongs to the Special Issue Biosensing Based on Nanohybrid Materials)
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Review

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20 pages, 4925 KiB  
Review
Patent Overview of Innovative Hyaluronic Acid-Based Hydrogel Biosensors
by Ahmed Fatimi, Fouad Damiri, Mohammed Berrada and Adina Magdalena Musuc
Biosensors 2024, 14(12), 567; https://doi.org/10.3390/bios14120567 - 24 Nov 2024
Cited by 1 | Viewed by 1541
Abstract
Hyaluronic acid-based hydrogels are emerging as highly versatile materials for cost-effective biosensors, capable of sensitive chemical and biological detection. These hydrogels, functionalized with specific groups, exhibit sensitivity modulated by factors such as temperature, pH, and analyte concentration, allowing for a broad spectrum of [...] Read more.
Hyaluronic acid-based hydrogels are emerging as highly versatile materials for cost-effective biosensors, capable of sensitive chemical and biological detection. These hydrogels, functionalized with specific groups, exhibit sensitivity modulated by factors such as temperature, pH, and analyte concentration, allowing for a broad spectrum of applications. This study presents a patent-centered overview of recent advancements in hyaluronic acid hydrogel biosensors from 2003 to 2023. A total of 50 patent documents—including 41 patent applications and 9 granted patents—reveal a growing interest, primarily driven by United States-based institutions, which account for approximately 54% of all filings. This trend reflects the strong collaboration between universities, industry, and foundations in pushing this technology forward. Most patented technologies focus on biosensors for in vivo blood analysis, measuring critical parameters such as gas concentration and pH, with particular emphasis on glucose monitoring via tissue impedance using enzyme-immobilized oxidase electrodes. Additionally, the 9 granted patents collectively showcase key innovations, highlighting applications from continuous glucose monitors to implantable vascular devices and sweat analyte detection systems. These patents underscore the adaptability and biocompatibility of hyaluronic acid hydrogels, reinforcing their role in enhancing biosensor performance for real-time health monitoring. In summary, this overview highlights the importance of patent analysis in tracking and directing research and development, helping to clarify the field’s evolution and identify innovation gaps for hyaluronic acid-based hydrogel biosensors. Full article
(This article belongs to the Special Issue Biosensing Based on Nanohybrid Materials)
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