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Biosensors
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Artificial Skins and Wearable Biosensors for Healthcare Monitoring
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Artificial Skins and Wearable Biosensors for Healthcare Monitoring

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (31 December 2024) | Viewed by 33425

Special Issue Editors

Prof. Dr. Yanchao Mao

E-Mail Website
Guest Editor
School of Physics and Microelectronics, Zhengzhou University, Zhengzhou 450001, China
Interests: ionic hydrogels; human–machine interaction sensors; stretchable sensors; bioelectronics
Special Issues, Collections and Topics in MDPI journals
Dr. Pengcheng Zhu

E-Mail Website
Guest Editor
School of Physics and Microelectronics, Zhengzhou University, Zhengzhou 450001, China
Interests: flexible and stretchable electronics; flexible thermoelectric devices for low-grade energy harvesting; piezoelectric nanogenerator; multifunctional sensors; e-skin; human-machine interfaces
Special Issues, Collections and Topics in MDPI journals
Dr. Lijun Lu

E-Mail Website
Guest Editor
School of Physics and Microelectronics, Zhengzhou University, Zhengzhou 450001, China
Interests: human–machine interaction sensor; flexible electronic skin; piezoelectric nanogenerator; flexible piezoresistive sensor; semiconductor device
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Artificial skin, also known as electronic skin (e-skin), refers to intelligent wearable electronics that simulate the tactile perception function of human skin to identify the detected external information changes through different electrical signals. Flexible e-skin can achieve a wide range of functions, such as the accurate detection and identification of pressure, strain, and temperature, which has greatly extended their application potential in the field of healthcare monitoring and human-machine interaction. At present, the current study on flexible tactile sensors is developing towards high resolution, high sensitivity, self-powering, visualization, biodegradability, and self-healing. However, considering the urgent demand and rapid application of flexible sensing technology in various emerging applications, there remains a great challenge in how to achieve quantification, multi-function, high stability, and durability in the actual detection process. This topic provides an excellent opportunity for those who are studying and working on the design and applications of wearable electronics. Research papers, review articles, and communications relating to the material development, structural design, mechanism interpretation, preparation process, and related circuit design of artificial skins are all invited to this Topic.

Prof. Dr. Yanchao Mao
Dr. Pengcheng Zhu
Dr. Lijun Lu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial skin
  • tactile sensor
  • wearable electronics
  • healthcare monitoring
  • human-machine interaction

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Related Special Issue

Published Papers (5 papers)

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Research

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9 pages, 1881 KiB  
Communication
Source Localization and Classification of Pulmonary Valve-Originated Electrocardiograms Using Volume Conductor Modeling with Anatomical Models
by Kota Ogawa and Akimasa Hirata
Biosensors 2024, 14(10), 513; https://doi.org/10.3390/bios14100513 - 21 Oct 2024
Cited by 2 | Viewed by 994
Abstract
Premature ventricular contractions (PVCs) are a common arrhythmia characterized by ectopic excitations within the ventricles. Accurately estimating the ablation site using an electrocardiogram (ECG) is crucial for the initial classification of PVC origins, typically focusing on the right and left ventricular outflow tracts. [...] Read more.
Premature ventricular contractions (PVCs) are a common arrhythmia characterized by ectopic excitations within the ventricles. Accurately estimating the ablation site using an electrocardiogram (ECG) is crucial for the initial classification of PVC origins, typically focusing on the right and left ventricular outflow tracts. However, finer classification, specifically identifying the left cusp (LC), anterior cusp (AC), and right cusp (RC), is essential for detailed preoperative planning. This study aims to improve the accuracy of cardiac waveform source estimation and classification in 27 patients with PVCs originating from the pulmonary valve. We utilized an anatomical human model and electromagnetic simulations to estimate wave source positions from 12-lead ECG data. Time-series source points were identified for each measured ECG waveform, focusing on the moment when the distance between the estimated wave source and the pulmonary valve was minimal. Computational analysis revealed that the distance between the estimated wave source and the pulmonary valve was reduced to less than 1 cm, with LC localization achieving errors under 5 mm. Additionally, 74.1% of the subjects were accurately classified into the correct origin (LC, AC, or RC), with each origin demonstrating the highest percentage of subjects corresponding to the targeted excitation origin. Our findings underscore the novel potential of this source localization method as a valuable complement to traditional waveform classification, offering enhanced diagnostic precision and improved preoperative planning for PVC ablation procedures. Full article
(This article belongs to the Special Issue Artificial Skins and Wearable Biosensors for Healthcare Monitoring)
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Review

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30 pages, 4599 KiB  
Review
Advances in Wearable Biosensors for Healthcare: Current Trends, Applications, and Future Perspectives
by Dang-Khoa Vo and Kieu The Loan Trinh
Biosensors 2024, 14(11), 560; https://doi.org/10.3390/bios14110560 - 18 Nov 2024
Cited by 10 | Viewed by 11828
Abstract
Wearable biosensors are a fast-evolving topic at the intersection of healthcare, technology, and personalized medicine. These sensors, which are frequently integrated into clothes and accessories or directly applied to the skin, provide continuous, real-time monitoring of physiological and biochemical parameters such as heart [...] Read more.
Wearable biosensors are a fast-evolving topic at the intersection of healthcare, technology, and personalized medicine. These sensors, which are frequently integrated into clothes and accessories or directly applied to the skin, provide continuous, real-time monitoring of physiological and biochemical parameters such as heart rate, glucose levels, and hydration status. Recent breakthroughs in downsizing, materials science, and wireless communication have greatly improved the functionality, comfort, and accessibility of wearable biosensors. This review examines the present status of wearable biosensor technology, with an emphasis on advances in sensor design, fabrication techniques, and data analysis algorithms. We analyze diverse applications in clinical diagnostics, chronic illness management, and fitness tracking, emphasizing their capacity to transform health monitoring and facilitate early disease diagnosis. Additionally, this review seeks to shed light on the future of wearable biosensors in healthcare and wellness by summarizing existing trends and new advancements. Full article
(This article belongs to the Special Issue Artificial Skins and Wearable Biosensors for Healthcare Monitoring)
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24 pages, 13114 KiB  
Review
Recent Advances in Natural-Polymer-Based Hydrogels for Body Movement and Biomedical Monitoring
by Jing Liu, Saisai Li, Shuoze Li, Jinyue Tian, Hang Li, Zhifeng Pan, Lijun Lu and Yanchao Mao
Biosensors 2024, 14(9), 415; https://doi.org/10.3390/bios14090415 - 27 Aug 2024
Cited by 3 | Viewed by 2185
Abstract
In recent years, the interest in medical monitoring for human health has been rapidly increasing due to widespread concern. Hydrogels are widely used in medical monitoring and other fields due to their excellent mechanical properties, electrical conductivity and adhesion. However, some of the [...] Read more.
In recent years, the interest in medical monitoring for human health has been rapidly increasing due to widespread concern. Hydrogels are widely used in medical monitoring and other fields due to their excellent mechanical properties, electrical conductivity and adhesion. However, some of the non-degradable materials in hydrogels may cause some environmental damage and resource waste. Therefore, organic renewable natural polymers with excellent properties of biocompatibility, biodegradability, low cost and non-toxicity are expected to serve as an alternative to those non-degradable materials, and also provide a broad application prospect for the development of natural-polymer-based hydrogels as flexible electronic devices. This paper reviews the progress of research on many different types of natural-polymer-based hydrogels such as proteins and polysaccharides. The applications of natural-polymer-based hydrogels in body movement detection and biomedical monitoring are then discussed. Finally, the present challenges and future prospects of natural polymer-based hydrogels are summarized. Full article
(This article belongs to the Special Issue Artificial Skins and Wearable Biosensors for Healthcare Monitoring)
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29 pages, 6877 KiB  
Review
Epidermal Wearable Biosensors for Monitoring Biomarkers of Chronic Disease in Sweat
by Xichen Yuan, Chen Li, Xu Yin, Yang Yang, Bowen Ji, Yinbo Niu and Li Ren
Biosensors 2023, 13(3), 313; https://doi.org/10.3390/bios13030313 - 23 Feb 2023
Cited by 23 | Viewed by 7234
Abstract
Biological information detection technology is mainly used for the detection of physiological and biochemical parameters closely related to human tissues and organ lesions, such as biomarkers. This technology has important value in the clinical diagnosis and treatment of chronic diseases in their early [...] Read more.
Biological information detection technology is mainly used for the detection of physiological and biochemical parameters closely related to human tissues and organ lesions, such as biomarkers. This technology has important value in the clinical diagnosis and treatment of chronic diseases in their early stages. Wearable biosensors can be integrated with the Internet of Things and Big Data to realize the detection, transmission, storage, and comprehensive analysis of human physiological and biochemical information. This technology has extremely wide applications and considerable market prospects in frontier fields including personal health monitoring, chronic disease diagnosis and management, and home medical care. In this review, we systematically summarized the sweat biomarkers, introduced the sweat extraction and collection methods, and discussed the application and development of epidermal wearable biosensors for monitoring biomarkers in sweat in preclinical research in recent years. In addition, the current challenges and development prospects in this field were discussed. Full article
(This article belongs to the Special Issue Artificial Skins and Wearable Biosensors for Healthcare Monitoring)
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26 pages, 6550 KiB  
Review
Flexible Textile-Based Sweat Sensors for Wearable Applications
by Jing Yin, Jingcheng Li, Vundrala Sumedha Reddy, Dongxiao Ji, Seeram Ramakrishna and Lan Xu
Biosensors 2023, 13(1), 127; https://doi.org/10.3390/bios13010127 - 12 Jan 2023
Cited by 46 | Viewed by 10360
Abstract
The current physical health care system has gradually evolved into a form of virtual hospitals communicating with sensors, which can not only save time but can also diagnose a patient’s physical condition in real time. Textile-based wearable sensors have recently been identified as [...] Read more.
The current physical health care system has gradually evolved into a form of virtual hospitals communicating with sensors, which can not only save time but can also diagnose a patient’s physical condition in real time. Textile-based wearable sensors have recently been identified as detection platforms with high potential. They are developed for the real-time noninvasive detection of human physiological information to comprehensively analyze the health status of the human body. Sweat comprises various chemical compositions, which can be used as biomarkers to reflect the relevant information of the human physiology, thus providing references for health conditions. Combined together, textile-based sweat sensors are more flexible and comfortable than other conventional sensors, making them easily integrated into the wearable field. In this short review, the research progress of textile-based flexible sweat sensors was reviewed. Three mechanisms commonly used for textile-based sweat sensors were firstly contrasted with an introduction to their materials and preparation processes. The components of textile-based sweat sensors, which mainly consist of a sweat transportation channel and collector, a signal-selection unit, sensing elements and sensor integration and communication technologies, were reviewed. The applications of textile-based sweat sensors with different mechanisms were also presented. Finally, the existing problems and challenges of sweat sensors were summarized, which may contribute to promote their further development. Full article
(This article belongs to the Special Issue Artificial Skins and Wearable Biosensors for Healthcare Monitoring)
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