Surface Plasmon Resonance-Based Biosensors and Their Applications
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".
Deadline for manuscript submissions: 1 November 2025 | Viewed by 3
Special Issue Editor
Special Issue Information
Dear Colleagues,
Surface plasmon resonance (SPR) refers to the quasi-particles of the collective oscillation of electrons and photons (electromagnetic waves) at metal–dielectric interfaces. SPR produces intense localized electromagnetic fields, leading to superior detection sensitivity. Various SPR-based methods have been shown to be information-rich tools for analyzing biological materials, with some offering exceedingly high sensitivity at the single-molecule level, and others enabling label-free, non-destructive, and in situ observation of various biological processes. SPR has also been shown to immobilize suspended entities such as biomolecules, akin in its underlying physics to the well-known optical tweezers.
Significant advances have been made over the past several decades in biomedical diagnostics, drug discovery, food safety, environmental monitoring, and beyond. Of special interest is subjects such as sensitivity beyond current detection limits to include subtleties such as secondary and tertiary conformational differences in proteins, the challenge of single-molecule/single-vesicle detection with sufficiently high throughput to ensure statistical significance, and the fundamental trade-offs between the ability to observe biological processes in situ at the single-molecule level (such as protein–protein interactions) and the unavoidable disturbance to the object under observation (such as denaturing proteins).
This Special Issue aims to provide a communication platform for researchers and technologists in this promising sub-field of research straddling biology, physics, and engineering, and to serve as a repository of information on the pertinent aspects of engineering and technology development, as well as cases of successful (or not so successful) applications. Ultimately, we hope to foster interdisciplinary collaboration and drive forward the continued growth of this exciting and bourgeoning field.
Prof. Dr. Ya-Hong Xie
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- surface plasmon resonance
- nano-structures
- biosensing
- drug discovery
- food safety
- environmental monitoring
- biomarker discovery
- diagnostic
- proteomics
- single-molecule detection
- machine learning
- protein folding
- label-free
- plasmonic tweezers
- sensitivity
- specificity
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
