Wearable Biosensors and Health Monitoring

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 1 November 2025 | Viewed by 1524

Special Issue Editors


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Guest Editor
School of Biological Sciences and Medical Engineering, Southeast University, Nanjing, China
Interests: ultrasonic transducer and related medical application; portable and wearable ultrasound systems; AI ultrasonic medical image processing

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Guest Editor
School of electronic Information, Central South University, Nanjing, China
Interests: wearable sensing; microfluidic chips and sensing; intelligent instruments and sensing; nano-loaded drugs and sensing

Special Issue Information

Dear Colleagues,

Wearable biosensors have emerged as powerful tools for continuous health monitoring, personalized medicine, and early disease detection. This Special Issue aims to explore the latest advancements in wearable biosensor technology and its applications in biomedical research and healthcare. We invite original research articles, reviews, and perspectives covering various aspects of wearable biosensors, including materials, fabrication techniques, sensor design, integration, data analytics, and clinical translation.

Topics of interest include, but are not limited to, the following:

  • Novel materials and fabrication methods for wearable biosensors;
  • Flexible and stretchable electronics for wearable sensor integration;
  • Biocompatible sensor interfaces and biofunctionalization strategies;
  • Advanced signal processing algorithms for real-time data analysis;
  • Wireless communication protocols and wearable sensor networks;
  • Integration of wearable biosensors with mobile health (mHealth) platforms;
  • Applications of wearable biosensors in disease monitoring, diagnosis, and management;
  • Wearable biosensors for monitoring physiological parameters (e.g., heart rate, blood pressure, and glucose levels);
  • Wearable biosensors for monitoring biochemical markers and biomarkers;
  • Wearable biosensors for tracking physical activity, sleep patterns, and overall wellness;
  • Clinical validation and translation of wearable biosensor technology;
  • Human factors, usability, and acceptability of wearable biosensors in healthcare settings.

Prof. Dr. Xiaoxiang Gao
Prof. Dr. Zhengchun Liu
Guest Editors

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Keywords

  • wearable biosensors
  • flexible and stretchable bioelectronics
  • AI in wearable biosensing
  • multimodal wearable biosensing
  • multimodal/multifunctional wearable biosensing
  • biocompatible materials
  • biosensing textiles
  • biofunctionalized surfaces
  • smart materials
  • graphene-based sensors
  • sensor integration
  • human–computer interactions
  • remote patient monitoring
  • wearable energy sources
  • signal processing algorithms
  • Internet of Diseases (IoD)

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Published Papers (2 papers)

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Research

10 pages, 1735 KiB  
Communication
Wearable Humidity Sensor Using Cs3Cu2I5 Metal Halides with Hydroxyl Selective Phase Transition for Breath Monitoring
by Si Hyeok Yang, Lim Kyung Oh, Dong Ho Lee, Donghoon Gwak, Nara Song, Bowon Oh, Na Young Lee, Hongki Kim, Han Seul Kim and Jin Woo Choi
Biosensors 2025, 15(5), 311; https://doi.org/10.3390/bios15050311 - 13 May 2025
Viewed by 207
Abstract
The low-dimensional metal halide Cs3Cu2I5 exhibits unique electrical and chemical properties. Notably, it undergoes a phase transition to CsCu2I3 upon exposure to hydroxyl (-OH) gas, resulting in significant changes in its electrical characteristics. In this [...] Read more.
The low-dimensional metal halide Cs3Cu2I5 exhibits unique electrical and chemical properties. Notably, it undergoes a phase transition to CsCu2I3 upon exposure to hydroxyl (-OH) gas, resulting in significant changes in its electrical characteristics. In this study, we developed a highly selective semiconductor-based gas sensor utilizing Cs3Cu2I5. The material was synthesized on an Al2O3 substrate with carbon electrodes using a solution-based process, enabling gas sensing based on its electrical properties. The sensor was further integrated into an Arduino-based real-time monitoring system for wearable applications. The final system was mounted onto a face mask, enabling the real-time detection of human respiration. This research presents a next-generation sensor platform for real-time respiratory monitoring, demonstrating the potential of Cs3Cu2I5 in advanced wearable bio-gas sensing applications. Full article
(This article belongs to the Special Issue Wearable Biosensors and Health Monitoring)
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18 pages, 5701 KiB  
Article
Glucose Sensor Design Based on Monte Carlo Simulation
by Gang Xue, Ruiping Zhang, Yihao Chen, Wei Xu and Changxing Zhang
Biosensors 2025, 15(1), 17; https://doi.org/10.3390/bios15010017 - 4 Jan 2025
Viewed by 1044
Abstract
Continuous glucose monitoring based on the minimally invasive implantation of glucose sensor is characterized by high accuracy and good stability. At present, glucose concentration monitoring based on fluorescent glucose capsule sensor is a new development trend. In this paper, we design a fluorescent [...] Read more.
Continuous glucose monitoring based on the minimally invasive implantation of glucose sensor is characterized by high accuracy and good stability. At present, glucose concentration monitoring based on fluorescent glucose capsule sensor is a new development trend. In this paper, we design a fluorescent glucose capsule sensor with a design optimization study. The motion trajectory of incident light in the fluorescent gel layer is simulated based on the Monte Carlo method, and the cloud maps of light intensity with the light intensity distribution at the light-receiving layer are plotted. Altering the density of fluorescent molecules, varying the thickness of tissue layers, and adjusting the angle of incidence deflection, the study investigates the influence of these parameter changes on the optimal position of reflected light at the bottom. Finally, the simulation results were utilized to design and fabricate a fluorescent glucose capsule sensor. Rabbit subcutaneous tissue glucose level tests and real-time glucose solution concentration monitoring experiments were performed. This work contributes to the real-time monitoring of glucose levels and opens up new avenues for research on fabricating glucose sensors. Full article
(This article belongs to the Special Issue Wearable Biosensors and Health Monitoring)
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